Effect of Hashimoto's thyroiditis on the extent of the ablation zone in early stages of ultrasound-guided radiofrequency ablation for papillary thyroid microcarcinoma: a large cohort study of 772 patients

Figures & data

Figure 1. Flow diagram of the study selection procedure.

Table 1. The demographic and ablation data of the selected patients and lesions.

	Total	PTMC	HT + PTMC	p Value
Patients	772	556	216
Lesions	797	573	224
Age (years)	40.8 ± 11.0	41.5 ± 11.1	38.8 ± 10.5	.001
Gender				.000
Male	151 (19.56%)	132 (23.74%)	19 (8.8%)
Female	621 (80.44%)	424 (76.26%)	197 (91.2%)
Maximum diameters (mm)	5.6 ± 1.8	5.5 ± 1.8	5.6 ± 1.8	.466
Volumes (mL)	0.078 ± 0.078	0.078 ± 0.079	0.078 ± 0.073	.775
Ablation time (s)	62.6 ± 42.7	61.1 ± 42.7	66.2 ± 55.5	.714
Ablation energy (kJ)	1.904 ± 1.576	1.880 ± 1.485	1.966 ± 1.792	.735

PTMC: papillary thyroid micro-carcinoma; HT: Hashimoto's thyroiditis.

Figure 2. Changes in maximum diameters in PTMC cases with/without HT. Error bar: 95% confidence interval; PTMC: papillary thyroid microcarcinoma; HT: Hashimoto's thyroiditis.

Table 2. The maximum diameters of the lesion before and after RFA (mm).

Time	PTMC		HT + PTMC		p Value
	Mean ± SD	Range	Mean ± SD	Range
Initially	5.5 ± 1.8	1.8–10.0	5.6 ± 1.8	2.1–10.0	.466
Immediately	14.0 ± 2.6*	7.6–24.3	14.0 ± 2.5*	7.6–24.3	.890
One day	16.1 ± 3.1*	8.9–30.4	15.8 ± 3.2*	7.6–28.9	.076
One week	15.2 ± 3.2*	5.9–28.4	14.6 ± 3.1*	4.7–27.9	.005

* Means p value <.05 (compared with the initial maximum diameters).

Figure 3. Changes in volumes in PTMC cases with/without HT. Error bar: 95% confidence interval; PTMC: papillary thyroid microcarcinoma; HT: Hashimoto's thyroiditis.

Table 3. The volumes of the lesion before and after RFA (mL).

Time	PTMC		HT + PTMC		p Value
	Mean ± SD	Range	Mean ± SD	Range
Initially	0.078 ± 0.079	0.003–0.99	0.078 ± 0.073	0.01–0.34	.775
Immediately	0.838 ± 0.426*	0.05–4.72	0.841 ± 0.434*	0.14–2.63	.633
One day	1.259 ± 0.624*	0.23–4.84	1.214 ± 0.629*	0.14–4.02	.189
One week	1.028 ± 0.540*	0.05–4.12	0.932 ± 0.498*	0.03–3.29	.007

* Means p value <.05 (compared with the initial volumes).