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ORIGINAL ARTICLE

Dose-effect models for risk – relationship to cell survival parameters

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Pages 829-835 | Received 01 Jun 2005, Published online: 08 Jul 2009

Figures & data

Figure 1.  Risk predictions according to the competition model for various assumptions regarding the magnitude of the inducible repair for cellular survival. Upper panel α/β = 10 Gy; middle panel α/β = 5 Gy; lower panel α/β = 3 Gy. (α1=0.05 Gy−1, SF2=70%, IRR1=1)

Figure 1.  Risk predictions according to the competition model for various assumptions regarding the magnitude of the inducible repair for cellular survival. Upper panel α/β = 10 Gy; middle panel α/β = 5 Gy; lower panel α/β = 3 Gy. (α1=0.05 Gy−1, SF2=70%, IRR1=1)

Figure 2.  Risk predictions according to the competition model for various assumptions regarding the magnitude of the inducible repair for induction of DNA mutations. Upper panel α/β = 10 Gy; middle panel α/β = 5 Gy; lower panel α/β = 3 Gy. (α1=0.05 GyP−1P, SF2=70%, IRRB2=6)

Figure 2.  Risk predictions according to the competition model for various assumptions regarding the magnitude of the inducible repair for induction of DNA mutations. Upper panel α/β = 10 Gy; middle panel α/β = 5 Gy; lower panel α/β = 3 Gy. (α1=0.05 GyP−1P, SF2=70%, IRRB2=6)

Figure 3.  Risk predictions according to the LQ-based competition model for various assumptions regarding the heterogeneity of cellular radiosensitivity. Upper panel α/β = 10 Gy; middle panel α/β = 5 Gy; lower panel α/β = 3 Gy. (αB1B=0.05 Gy−1P, SF2=70%).

Figure 3.  Risk predictions according to the LQ-based competition model for various assumptions regarding the heterogeneity of cellular radiosensitivity. Upper panel α/β = 10 Gy; middle panel α/β = 5 Gy; lower panel α/β = 3 Gy. (αB1B=0.05 Gy−1P, SF2=70%).

Figure 4.  Risk predictions according to the LQ-based competition model for various assumptions regarding the α/β values. (αB1B=0.05 Gy−1, αB2B=0.25 Gy−1)

Figure 4.  Risk predictions according to the LQ-based competition model for various assumptions regarding the α/β values. (αB1B=0.05 Gy−1, αB2B=0.25 Gy−1)

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