http://orcid.org/0000-0003-3829-0210
Figures & data
Figure 1. Electrochemotherapy treatment and follow-up. The left and middle panels are from the first electroporation procedure. A linear array electrode was used, coupled to a square wave pulse generator. Treatment commenced 8 min after i.v. bleomycin infusion and the tumor was manually palpated after which electrodes were sequentially applied to cover the tumor volume. Right panel: At 1-year follow-up, hyperpigmentation in the treated area is just visible.
Figure 2. MRI before, during and after the treatment period. (A) (1 and 2): January 2016; baseline before the first treatment with electrochemotherapy, the tumor is measuring 7.1 × 2.2 cm. (B) (1 and 2): March 2016; after the first treatment with electrochemotherapy, the tumor is measuring 6.0 × 2.2 cm. (C) (1 and 2): January 2017; 1-year follow-up after the second treatment with electrochemotherapy. The tumor is measuring 2.9 × 1.7 cm.
Figure 3. Pain score using the NRS scale, and use of pain medication. Using the numeric rating scale (NRS), from 0 (no pain) to 10 (worst imaginable pain), the patient was asked to describe pain before, during and after electrochemotherapy. Initially, the patient was taking pain medication (gabapentin, tramadol), and continued to do so until her pain score was down to 2, after which this was discontinued (period of pain medication shown on graph). In conclusion, the NRS pain score went from 7 with gabapentin and tramadol to 2 without pain medication after electrochemotherapy.
