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Original Article

Elevated levels of thymidine kinase 1 peptide in serum from patients with breast cancer

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Pages 116-120 | Received 05 Dec 2008, Published online: 12 Jul 2009

Figures & data

Figure 1.  Receiver operating characteristics (ROC) curves for thymidine kinase 1 (TK1) analysed in serum samples from patients with breast cancer (n=24) collected four weeks after surgery in comparison with healthy controls (n=100). Area under the curve (AUC) = 0.56, 95% confidence interval (CI) 0.47–0.65, P=0.34.

Figure 1.  Receiver operating characteristics (ROC) curves for thymidine kinase 1 (TK1) analysed in serum samples from patients with breast cancer (n=24) collected four weeks after surgery in comparison with healthy controls (n=100). Area under the curve (AUC) = 0.56, 95% confidence interval (CI) 0.47–0.65, P=0.34.

Figure 2.  Receiver operating characteristics (ROC) curves for thymidine kinase 1 (TK1) analysed in serum samples from patients with breast cancer (n=39) collected after metastatic tumour recurrence after surgery in comparison with healthy controls (n=100). Area under the curve (AUC) = 0.73, 95% confidence interval (CI) 0.65–0.80, P<0.0001.

Figure 2.  Receiver operating characteristics (ROC) curves for thymidine kinase 1 (TK1) analysed in serum samples from patients with breast cancer (n=39) collected after metastatic tumour recurrence after surgery in comparison with healthy controls (n=100). Area under the curve (AUC) = 0.73, 95% confidence interval (CI) 0.65–0.80, P<0.0001.

Figure 3.  Receiver operating characteristics (ROC) curves for thymidine kinase 1 (TK1) analysed in serum samples from patients with breast cancer (n=41) collected after chemotherapy in comparison with healthy controls (n=100). AUC = 0.64, 95% CI 0.56–0.72, P = 0.0076.

Figure 3.  Receiver operating characteristics (ROC) curves for thymidine kinase 1 (TK1) analysed in serum samples from patients with breast cancer (n=41) collected after chemotherapy in comparison with healthy controls (n=100). AUC = 0.64, 95% CI 0.56–0.72, P = 0.0076.

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