Evaluation of right heart function changes in patients with pulmonary hypertension via two-dimensional speckle tracking imaging: a retrospective study

Figures & data

Table 1. Comparison of General information ($\overline{x}$ ± s).

Parameters	Control group (n = 40)	Case group (n = 74)
		A (n = 25)	B(n = 31)	C(n = 18)
Pulmonary arterial systolic pressure (mmHg)	23.98 ± 7.89	44.20 ± 4.05	57.03 ± 4.69	92.33 ± 8.72
Age (years)	47.45 ± 12.33	52.24 ± 12.65	52.13 ± 11.45	51.23 ± 10.34
Heart rate (beats/min)	75.23 ± 10.45	77.34 ± 10.11	83.67 ± 10.45^*△	90.43 ± 10.57^*△△▲
Gender (female/male)	25/15	14/11	19/12	9/9
Systolic pressure (mmHg)	115.57 ± 12.58	117.34 ± 13.82	119.35 ± 12.45	120.39 ± 11.38
Diastolic pressure (mmHg)	73.43 ± 8.47	73.13 ± 8.66	74.65 ± 9.32	75.49 ± 7.98
LVEF	65.43 ± 3.60	66.82 ± 3.61	64.68 ± 4.34	67.18 ± 5.26

Note: *p < 0.01 compared with the control group; ^△p < 0.05, ^△△p < 0.01 compared with the A group; ^▲p < 0.05 compared with the B group.

Table 2. Comparison of common right heart echocardiographic parameters ($\overline{x}$ ± s).

Parameters	Control group (n = 40)	Case group (n = 74)
		A(n = 25)	B(n = 31)	C(n = 18)
Right ventricular wall thickness (mm)	3.24 ± 0.53	3.32 ± 0.48	4.84 ± 0.50^**△△	5.65 ± 0.61^**△△▲▲
RVEDA (cm^2)	14.41 ± 2.47	14.19 ± 2.17	18.32 ± 2.64^**△△	22.69 ± 2.58^**△△▲▲
RVESA (cm^2)	7.69 ± 2.38	7.81 ± 2.21	11.07 ± 2.54^**△△	15.78 ± 3.25^**△△▲▲
RVFAC (%)	47.82 ± 7.75	46.14 ± 8.81	40.34 ± 6.08^**△△	31.05 ± 6.62^**△△▲▲
TAPSE(mm)	23.67 ± 2.81	23.24 ± 3.87	17.78 ± 3.26^**△△	13.55 ± 3.65^**△△▲▲
S´(cm/s)	13.77 ± 2.73	14.68 ± 2.71	11.79 ± 2.34^*△△	8.52 ± 1.91^**△△▲▲

Note: *p < 0.05, ** p < 0.01 compared with the control group; ^△p < 0.05, ^△△p < 0.01 compared with the A group; ^▲p < 0.05, ^▲▲p < 0.01 compared with the B group.

RVEDA: right ventricular end-diastolic area; RVESA: right ventricular end-systolic area; RVFAC: right ventricular fractional area change; TAPSE: Tricuspid annular plane systolic excursion; S': tricuspid annular peak systolic velocity.

Table 3. Comparison of longitudinal strain parameters in the right ventricle ($\overline{x}$ ± s).

	Control group (n = 40)	Case group (n = 74)
		A(n = 25)	B(n = 31)	C(n = 18)
Free wall (whole)	−23.03 ± 6.10	−21.29 ± 5.39*	−17.33 ± 5.25*^*△△	−13.59 ± 5.08*^*△△▲
Basal segment	−24.87 ± 5.84	−22.19 ± 5.50*	−17.44 ± 4.13^**△△	−13.39 ± 4.58^**△△▲▲
Middle segment	−22.47 ± 6.37	−19.29 ± 4.65*	−16.05 ± 5.36^**△	−12.71 ± 3.93^**△△^▲
Apical segment	−21.75 ± 5.79	−22.39 ± 5.61	−18.49 ± 5.98^*△△	−14.68 ± 6.49^**△△▲

Note: *p < 0.05, **p < 0.01 compared with the control group; ^△p < 0.05, ^△△p < 0.01 compared with the A group; ^▲p < 0.05, ^▲▲p < 0.01 compared with the B group.

Figure 1. A: the diagram of Intra-observer consistency analysis; B: Inter-observer consistency analysis diagram.

Availability of data and materials

The datasets used and analysed during the current study available from the corresponding author on reasonable request.