Burkholderia cepacia complex in cystic fibrosis: critical gaps in diagnosis and therapy

Figures & data

Figure 1. Bcc growth and colonial isolation on BCSA medium. BCSA agar plate seeded by cross streaking with a Bcc strain showing yellow colour in the section with bacterial growth (Taken from Landes N. et al. 2016 under the terms and conditions of licence number 5687200897100 (ELSEVIER)).

Table 1. Updated antibiogram published by EUCAST until december 2023 (modified from https://mic.eucast.org/search/).

Antibiotic	MIC (µg·mL^-1)																			Observations	Confidence Interval
	0.002	0.004	0.008	0.016	0.03	0.06	0.125	0.025	0.5	1	2	4	8	16	32	64	128	256	512
FPZ	0	0	0	0	0	0	0	2	1	4	34	32	28	8	2	2	0	0	0	113	ID
CAZ	0	0	0	0	0	0	0	1	5	13	20	9	5	2	8	3	4	1	0	71	0.25-256
CTB	0	0	0	0	0	0	0	0	1	2	6	3	0	0	0	1	0	2	0	15	ID
LEV	0	0	0	0	0	0	0	0	0	4	9	3	0	1	0	0	0	0	0	17	ID
MEM	0	0	0	0	0	1	2	8	4	12	23	17	4	5	0	5	0	0	0	81	ID
MXF	0	0	0	0	0	1	2	5	2	0	1	2	0	0	2	0	0	0	0	15	ID
TZP	0	0	0	1	0	0	1	6	18	12	6	6	5	3	2	3	5	1	1	70	0.125-16
TEM	0	0	0	0	0	0	0	0	0	3	12	30	43	32	17	3	6	1	0	147	2-1024
TM	0	0	0	0	0	0	1	0	1	0	6	2	2	11	4	4	6	3	0	40	ID
SXT	0	0	0	0	0	0	0	4	4	2	5	2	0	0	0	0	0	0	0	17	ID

FPZ = Cefepime-zidebactam; CAZ = Ceftazidime; CTB = Ceftibuten; LEV = Levofloxacin; MEM = Meropenem; MXF = Moxifloxacin; TZP = Piperacillin-tazobactam; TEM = Temocillin; TM = Tobramycin; SXT = Trimethoprim-sulfametoxazole; ID = Insufficient data.

Data availability statement

The data presented in this review were taken from published literature on public domains and therefore data sharing is not applicable to this article, as no new data were created or analysed in this study.