Body mass index and weight loss as risk factors for poor outcomes in patients with idiopathic pulmonary fibrosis: a systematic review and meta-analysis

Figures & data

Figure 1. Diagram of the preferred reporting items for systematic review and meta-analysis (PRISMA).

Figure 2. The forest plot pooled the hazard ratio of BMI predicting mortality in IPF.

Figure 3. The forest plot pooled the hazard ratio of BMI predicting acute exacerbation in IPF.

Figure 4. The forest plot pooled the hazard ratio of BMI predicting hospitalization in IPF.

Figure 5. The forest plot pooled the odds ratio of weight loss predicting mortality in IPF.

Figure 6. The forest plot pooled the hazard ratio of weight loss predicting mortality in IPF.

Figure 7. Funnel plots of trim-and-fill analysis (A: univariable; B: multivariable) for hazard ratio predicting mortality in IPF.

Table 1. Egger’s test for studies on BMI and weight loss predicting mortality, acute exacerbation and hospitalization in patients with IPF.

Group	nStudy	t	P
BMI and mortality(Univariate)	26	−2.54	0.018
BMI and mortality(Multivariable)	13	−2.37	0.037
BMI and acute exacerbation	5	1.66	0.195
BMI and hospitalization	3	−1.74	0.331
HR for weight loss and mortality	4	−2.69	0.115
OR for weight loss and mortality	5	0.39	0.721

Data availability statement

The original data presented in the study are included in the article/Supplementary Material, further inquiries can be directed to the corresponding author.