Figures & data
Figure 1. Effects of 6‐month regimen of low‐dose doxycycline (LDD; B = before, A = after) or placebo on plasma levels of pro‐inflammatory biomarkers in patients (n = 30) with acute coronary syndromes (ACS). (a): MMP‐8; (b): MMP‐9; (c): C‐reactive protein (CRP). MMP‐8 and ‐9 values represent densitometric scanning units and CRP represent µg/mL, and are expressed as means + SDs. (MMP = matrix metalloproteinases.)
Figure 2. Test positive result of the MMP‐8 specific chair‐side dip‐stick is confirmed with the appearance of the blue line in the catching zone (left, indicated by arrows). (MMP = matrix metalloproteinases.)
Figure 3. Scattergram of periodontitis patients' sites (n = 133) at baseline; correlation of MMP‐8 concentration (assessed by IFMA, µg/L) and MMP‐8 specific chair‐side dipstick test results (0 = negative; 1 = +; 2 = ++; 3 = +++). (IFMA = time‐resolved immunofluorometric assay; MMP = matrix metalloproteinases.)
Figure 4. MMP‐8 concentration in GCF (µg/L, bars) collected from 5–8 distinct sites from periodontitis patients (n = 8) and assessed by IFMA and MMP‐8 specific chair‐side dipstick test (−; +; ++ and +++) precede loss of attachment (AL, mm) during maintenance phase of periodontal treatment (scaling and root planing). MMP‐8 concentrations and AL are represented as means. (GCF = gingival crevicular fluid; IFMA = time‐resolved immunofluorometric assay; MMP = matrix metalloproteinases.)
