Prevalence of SENV-H and SENV-D Virus: Epidemiological Study in Blood Donors and Dialysis Patients

Figures & data

Figure 1 Age distribution in blood donors. N.E. = Normal expected.

Figure 2 Age distribution in dialysis patients. N.E. = Normal expected.

Table 1 Dialysis patients: HBV- and HCV-positive patients

Units of dialysis	Number of patients	HBV+	HCV+^†
Unit of dialysis A	18	2 (11.1%)	9 (50%)
Unit of dialysis B	23	1 (4.3%)	1 (4.3%)
Unit of dialysis C	47	1 (2.1%)	13 (27.7%)
Total	88	4 (4.5%)	23 (26.1%)

*age ranged 37 and 58 years; all males.

^†age ranged 44 and 85 years (65.1(13.2): 14 males (29.2%) 9 females (22.5%).

Table 2 Contingence tables and risk measures for SENV-H

	HBV+ or HCV+ −		TOT		HCV+	HCV−	TOT
SENV+	15	12	27		12	15	27
SENV-	12	49	61		11	50	61
TOT	27	61	88		23	65	88
PREVALENCE %	55.6	19.7	p < 0.001		52.1	23.1	p<0.05
C.I. 95%	36.86 –74.34	9.72 –29.68		C.I. 95%	31.76–72.59	13.90–34.58
RR 2.8 (C.I 95 % 1.55–5.214)				RR 2.26 (C.I. 95% 1.65–3.09)
AR 36.3%				AR 29%

Table 3 Contingence tables and risk measures for SENV-D

	HBV+ or HCV+	HBV− or HCV−	TOT		HCV+	HCV−	TOT
SENV+	6	6	12		6	6	12
SENV−	4	72	76		0	76	76
TOT	10	78	88		6	82	88
PREVALENCE %	60	7.7	p =5.6E–6		100	7.32	p =1.7E–10
C.I. 95%	21.71–78.29	0.24–10.28		C.I. 95%	21.71–78.29
RR 7.79 (C.I. 95% 3.21–18.91)				RR 13.66 (C.I. 95% 6.12–30.47)
AR 52.3%				AR 92.6%

Table 4 Dialysis patients: gender distribution in SENV-H and SENV-D positive patients

	SENV-H					SENV-D
	Total	+	−	Prevalence %	C.I. 95%	+	−	Total	Prevalence%	C.I. 95%
Males	16	32	48	33.3	19.97–46.63	3	45	48	6.25	−0.6–13.1
Females	11	29	40	27.5	13.66–41.34	9	31	40	22.50	9.56–35,4
Total	27	61	88			11	76	88
				p= n.s.					p < 0.05

Table 5 Dialysis patients: age distribution in HBV− and HCV-positive patients

Age	HBV/HCV+	HBV/HCV−	Prevalence %	C.I. 95%
≤40	1	7	12.5	−10.4–35.42
41–60	12	13	48.0	28.42–67.58
>61	14	41	25.4	13.94–36.97
Total	27	61
			p= n.s

Table 6 Dialysis patients: SENV-H and SENV-D results in dialysis units (A, B, and C)

		SENV-H					SENV-D
Dialysis unit	Median age	+	−	Total	Prevalence%	C. I. 95%	+	−	Total	Prevalence %	C.I. 95%
A	63.5	8	10	18	44.4	21.45–67.35	5	13	18	27.7	7.09–48.47
B	73	3	20	23	13.04	6.02–20.06	1	22	23	4.35	−3.99–12.68
C	66	16	31	47	34.04	20.5–47.58	6	41	47	12.76	3.22–22.31
Total		27	61	88			12	76	88
						p = n.s.					p = n.s.

Figure 3 The electropherograms show: A) SENV-H gene from nt 1266 (NCBI accession number AY206683); B) SENV-D gene from nt 1474 (NCBI accession number AB059352).