Effect of Fractional Urea Clearance on Survival of Hemodialysis Patients in Relation to Gender

Figures & data

Table 1 Clinical and laboratory characteristics of 146 patients undergoing hemodialysis according to gender and Kt/V

Groups(n)	Age(years)	Creatinine(mg/dL)	Albumin (g/dL)	Hematocrit (%)	Diabetic patients(%)
G1M (13)	52.7 ± 21.9	7.2 (6.2–9.0)	3.3 ± 0.4	30.4 ± 3.6	46
G2M (12)	51.7 ± 13.3	8.2 (7.0–10.4)	3.4 ± 0.4	29.5 ± 4.8	17
G3M (35)	53.3 ± 15.0	10.2 (8.3–11.1)	3.6 ± 0.4	31.3 ± 4.3	23
G1H (41)	57.5 ± 15.5	9.6 (8.0–11.6)	3.7 ± 0.5	31.1 ± 4.6	22
G2H (29)	56.0 ± 13.9	11.5 (8.1–12.6)	3.6 ± 0.4	32.2 ± 5.4	17
G3H (16)	57 ± 18.6	10.0 (8.9–11.8)	3.7 ± 0.3	31.5 ± 3.4	19
p	0.775	0.007	0.104	0.588	0.417

*p < 0.05 G2H vs. G1M.

Table 2 Mean, standard deviation and Cox multiple regression significance levels (independent prognostic impact on survival) of the different clinical and laboratory characteristics

	Males		Females
	Mean ± SD	Survival (p), Cox	Mean ± SD	Survival (p), Cox
Kt/V	1.22 ± 0.2	0.03	1.42 ± 0.3	0.005
Albumin (g/dL)	3.6 ± 0.4	0.05	3.5 ± 0.4	0.001
Creatinine (mg/dL)	10.2 ± 2.9	NS	8.9 ± 2.1	0.008
Age (years)	57 ± 15	0.07	53 ± 16	NS
Hematocrit (%)	31.6 ± 4.7	NS	30.8 ± 4.3	NS
Diabetes (%)	26	NS	20.5	NS

Table 3 Survival percent over time of 146 patients under hemodialysis according to gender and Kt/V

	Time (in months)
Groups (n)	12	24	36	48	60
G1M (13)	34	5	0	0	0
G2M (12)	75	61	61	61	61
G3M (35)	94	90	90	90	90
G1H (41)	70	58	58	58	58
G2H (29)	96	87	74	61	54
G3H (16)	93	84	84	84	84

*p < 0.05 in relation to the same period for the group with immediately smaller Kt/V.

Abbreviations: G1  =  Kt/V £ 1.2, G2  = 1.2 < Kt/V < 1.4, G3 = Kt/V ≥ 1.4, M  =  females, H = males.

Figure 1. Survival over 12 months of 146 patients under hemodialysis according to spKt/V and gender.

Figure 2. Survival over 24 months of 146 patients under hemodialysis according to spKt/V and gender.

Figure 3. Survival over 60 months of 146 patients under hemodialysis according to spKt/V and gender.