Altered Vascular Homeostasis in Type 2 Diabetic Nephropathy

Figures & data

Table 1 Vascular homeostasis in type 2 diabetic nephropathy

	Diabetic nephropathy	Normal	p value
Biomarker of vascular injury
Circulating endothelial cells	2010 ± 798	102 ± 112	< 0.001
Biomarkers of vascular repair, angiogenic factors
VEGF, pg/mL	219 ± 229	230 ± 220	NS
Angiopoietin-1, pg/mL	23721 ± 9731	52366 ± 32409	< 0.01
flt-1, pg/mL	33 ± 17	55 ± 11	< 0.01
Biomarkers of vascular repair, antiangiogenic factors
Angiopoietin-2, pg/mL	4588 ± 2225	1150 ± 1120	< 0.05
KDR, pg/mL	10414 ± 2198	7696 ± 1892	< 0.001

Figure 1. Normal vascular homeostasis.

Figure 2. Impaired angiogenesis in type 2 diabetic nephropathy.