Highly Successful and Low-Cost Desensitization Regime for Sensitized Living Donor Renal Transplant Recipients

Figures & data

Table 1 Demographic, pre- and post-treatment PRA and XM, and post-transplant follow-up details of the study group

S Number	Age	Sex	Donor	HLA match	Pre-treatment PRA in %	Pre-treatment XM in %	Post-treatment PRA in %	Post-treatment XM in %	Date oftransplant	Outcome	Rejection	Last creatinine	Follow-up (in months)
1	30	M	Sister	3/6	100	<10	2.5	<10	13.12.06	Well	None	1.3	17
2	37	M	Wife	3/4	65	<10	0	<10	3.01.07	Well	None	1.2	16
3	23	M	Father	3/6	65	<10	10	<10	21.02.07	Well	None	1.1	15
4	58	M	Wife	1/4	ND	40	7.5	<10	07.03.07	Died after three months of pulmonary embolism	None	1.6	3
5	29	F	Sister	3/6	85	100	0	<10	11.04.07	Well	None	1.1	13
6	40	M	Wife	0/4	100	<10	97.5	<10	On dialysis	—	—	—
7	50	M	Wife	0/4	40	20	0	<10	20.04.07	Graft vein thrombosis	—	Graft loss	0
8	42	F	Son	3/6	72.5	100	2.5	<10	25.04.07	Well	On PB	1.2	13
9	39	M	Wife	1/4	52.5	<10	0	<10	6.06.07	Well	On PB	0.9	11
10	38	F	Husband	0/4	100	<10	0	<10	29.06.07	Well	None	1.0	11
11	49	M	Wife	0/4	75	<10	7.5	<10	18.07.07	Died after two months of septicemia	None	2.3	2
12	45	M	Wife	0/4	62.5	20	0	<10	7.05.08	Well	None	1.2	1

*Not transplanted due to persistently high PRA.

Abbreviations: PB = protocol biopsy, ND = not done.

Table 2 HLA profile of recipients and donors

S Number	Donor relation	Recipient						Donor						HLA match
		A	A	B	B	DR	DR	A	A	B	B	DR	DR
1	Sister	3	11	13	60	5	13	33	11	35	60	7	13	3/6
2	Wife	3	11	51	61	ND	ND	3	11	51	49	ND	ND	3/4
3	Father	3	31	51	8	14	15	3	3	51	51	3	14	3/6
4	Wife	31	33	27	57	ND	ND	1	2	27	81	ND	ND	1/4
5	Sister	11	26	52	13	15	11	11	28	52	57	15	3	3/6
6	Wife	34	33	51	51	ND	ND	3	26	27	61	ND	ND	0/4
7	Wife	23	23	44	35	ND	ND	1	11	57	57	ND	ND	0/4
8	Son	3	3	51	63	12	15	2	3	60	63	12	13	3/6
9	Wife	26	32	8	51	ND	ND	1	66	8	37	ND	ND	1/4
10	Husband	2	28	51	8	ND	ND	9	11	35	35	ND	ND	0/4
11	Wife	1	28	44	57	ND	ND	1	11	51	62	ND	ND	0/4
12	Wife	11	24	35	61	ND	ND	3	3	27	27	ND	ND	0/4

*Not transplanted due to persistently high PRA.

Abbreviation: ND = not done.