The Effects of Low-Dose Erythropoiesis-Stimulating Agents on Peritoneal Fibrosis Induced by Chemical Peritonitis and on Peritoneal Tissue MMP–2 and TIMP–2 Levels in Rats

Figures & data

Table 1 Statistical analysis of groups for peritoneal thicknesses, inflammation score, and vascularization score area percentages as mean ± SD

Groups	Control	CH	CH+ESA	p value
Peritoneal thickness (μm)	8.02 ± 2.89	146.74 ± 26.1	48.12 ± 16.8	<0.001^abc
Inflammation scores	0.00 ± 0.00	2.25 ± 0.70	1.50 ± 0.75	<0.001^abc
Vasculopathy scores	0.12 ± 0.25	0.25 ± 0.32	0.25 ± 0.6	NS^abc

Significance: ^abetween CH and ESA groups, ^bbetween CH and control groups, ^cbetween ESA and control groups statistical comparison.

Abbreviation: NS = not significant.

Figure 1. Histopathologic images of peritoneal thickness: (A) Control group, ×20, (B) CH group, ×20, (C) ESA group original magnification, ×20.

Figure 2. Statistical analysis of groups for mean peritoneal tissue MMP–2 scores.

Figure 3. Statistical analysis of groups for mean peritoneal tissue TIMP–2 scores.