The value of bioimpedance analysis in the assessment of hydration and nutritional status in children on chronic peritoneal dialysis

Figures & data

Table 1. Distribution of baseline data.

	PD
N	84
Male	42 (50.00%)
Age	9.74 ± 4.54
Disease category
CAKUT	15 (17.86%)
SRNS	36 (42.86%)
Chronic glomerulonephritis	4 (4.76%)
Ciliopathy	8 (9.52%)
Nephrolithiasis	2 (2.38%)
Immune-related kidney diseases	9 (10.72%)
Other	2 (2.38%)
Unknown etiology	8 (9.52%)
Height - Z score	−1.57 ± 1.58
Weight - Z score	−1.47 ± 1.36
BMI - Z score	−1.01 (−2.20, 0.23)
SBP - Z score	2.35 ± 1.92
DBP - Z score	2.18 ± 1.79
PP (mmHg)	41.80 ± 9.51
Alb (g/L)	33.68 ± 6.76
Hb (g/L)	104.79 ± 27.70
LVMI (g/m^2.7)	43.55 (35.60, 59.80)
LVH	40 (47.60%)
Re-OH (%)	8.69 ± 17.35
Re-OH < −7% (N)	11
Re-OH −7% ∼ 7% (N)	26
Re-OH 7% ∼ 15% (N)	16
Re-OH > 15% (N)	31
LTI (kg/m^2)^a	12.55 ± 2.11
Lower LTI (N)	26
Normal LTI (N)	31
Higher LTI (N)	8

a: Due to the BIA-BCM machine detection, only 63 children with PD had valid LTI detection values. SRNS: steroid-resistant nephrotic syndrome; CAKUT: congenital anomalies of the kidney and urinary tract; PD: peritoneal dialysis; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; PP: pulse pressure; Alb: albumin; Hb: hemoglobin; LVMI: left ventricular mass index; LVH: left ventricular hypertrophy; Re-OH: relative OH; LTI: lean tissue index.

Figure 1. Correlation of Re-OH with BP. (A) Correlation of Re-OH with BP; (B; C) ROC correlation analysis of the Re-OH > 5.6% and Re-OH ≤ 5.6% subgroups in SBP value and SBPz value; (D). ROC correlation analysis. PD: peritoneal dialysis; SBP: systolic blood pressure; SBPz: systolic blood pressure z-score; Re-OH: relative OH.

Figure 2. Correlation of LTI with BMI. (A) Correlation of LTI with BMI. (B; C) ROC correlation analysis of the LTI > 12 kg/m² and LTI ≤ 12 kg/m² subgroups in BMI value and BMIz value; (D) ROC correlation analysis. PD: peritoneal dialysis; BMI: body mass index; BMIz: body mass index z score; LTI: lean tissue index.

Figure 3. Canonical correlation analysis of the relationship between the BIA-BCM indicator and the clinical indicator in the PD group. (A) BIA-BCM hydration indicator and the clinical hydration indicator. (B) BIA-BCM nutritional indicator and the clinical nutritional indicator. BIA-BCM, bioimpedance analysis-body composition monitor; PD: peritoneal dialysis; Hb: hemoglobin; LVMI: left ventricular mass index; SBPz: systolic blood pressure z-score; SBP: systolic blood pressure; DBP: diastolic blood pressure; PP: pulse pressure; OH: overhydration; Re-OH: relative OH; ECW: extracellular water; ICW: intracellular water; E/I, ECW to ICW ratio; CRP: C-reactive protein; TC: total cholesterol; TG, triglyceride; PAB, prealbumin; TP: total protein; Alb: albumin; HZ: heigh z-score; GR: growth rate; WZ, weight z-score; BMI: body mass index; BMIz: body mass index z score; LTI: lean tissue index; LTM: lean tissue mass; FTI: fat tissue index; ATM: adipose tissue mass.