Features of cardiovascular magnetic resonance native T1 mapping in maintenance hemodialysis patients and their related factors

Figures & data

Table 1. Baseline Demographic characteristics and clinical data for the patients on HD and healthy controls.

Variable	HD patients(n = 32)	Healthy controls(n = 14)	p Value
Gender (Female,%)	68.6	64.2	0.766
Age(years)	57.9 ± 11.3	43.1 ± 10.9	<0.001
Dialysis parameters
Duration of dialysis (months)	83.3 ± 57.7
Dry weight(kg)	61.7 ± 11.9
Ultrafiltration volume	2.4 ± 0.9
Laboratory examination
Hemoglobin(g/L)	120.4 ± 13.8	135.4 ± 10.2	<0.001
Hematocrit(%)	37.1 ± 4.2	45.1 ± 3.8	<0.001
Albumin(g/L)	36.3 ± 2.9	44.6 ± 5.4	<0.001
Serum creatinine(umol/L)	946.5 ± 188.3	79.3 ± 12.3	<0.001
Blood urea nitrogen (mmol/L)	27.3 ± 6.5	5.1 ± 1.6	<0.001
Uric acid (umol/L)	376.0 ± 70.3	305.2 ± 30.4	<0.001
Cholesterol(mmol/L)	4.4 ± 0.9
High density lipoprotein(mmol/L)	1.1 ± 0.3
Low density lipoprotein(mmol/L)	2.4 ± 0.8
Triglycerides(mmol/L)	1.8 ± 1.3
Lipoprotein a(mg/dL)	21.4 ± 20.8
Intact parathyroid hormone(pg/mL)	481.6 ± 313.6
Homocysteine(umol/L)	26.0 ± 9.2
High sensitivity C-reactive protein(mg/L)	3.5 ± 3.6
Calcium(mmol/L)	2.2 ± 0.2
Phosphorus(mmol/L)	2.1 ± 0.5
Calcium-phosphorus product	4.8 ± 1.4
Sodium(mmol/L)	137.8 ± 2.6
Potassium(mmol/L)	5.4 ± 0.8
N-terminal fragment pro-brain natriuretic peptide (pg/ml)	10657 ± 11859.7

Data are presented as percentage [number of participants] or mean ± SD, as appropriate.

Figure 1. Comparison of the global native T1 value between the HD group (n = 32) and the healthy control group (n = 14).

Figure 2. Comparison of native T1 values of left ventricular segments in the HD group (n = 32).

Figure 3. Graphs illustrate the correlation between the global native T1 value and laboratory, cardiac parameters in patients on HD. The correlation was analyzed between the global native T1 value and A, intact parathyroid hormone, B, left ventricular end-diastolic volume indexed to body surface area, C, left ventricular mass indexed to body surface area, and D, left ventricular ejection fraction.

Table 2. Correlation analysis of the global native T1 value.

Variable	Pearson coefficient	p Value
Duration of dialysis	−0.125	0.495
Dry weight	−0.020	0.961
Ultrafiltration volume	0.099	0.588
Hemoglobin	−0.091	0.619
Hematocrit	−0.089	0.628
Albumin	−0.281	0.120
Serum creatinine	−0.156	0.395
Blood urea nitrogen	−0.251	0.165
Uric acid	−0.224	0.217
Cholesterol	0.130	0.480
High sensitivity C-reactive protein	0.241	0.184
Low density lipoprotein	0.215	0.238
Triglycerides	−0.366	0.039
Lipoprotein a	0.067	0.717
Intact parathyroid hormone	0.418	0.017
Homocysteine	0.074	0.689
High sensitivity C-reactive protein	−0.043	0.816
Calcium	0.211	0.247
Phosphorus	0.109	0.553
Calcium-phosphorus product	0.161	0.378
Sodium	0.354	0.057
Potassium	−0.015	0.936
N-terminal fragment pro-brain natriuretic peptide	0.212	0.243
44-h average SBP	0.204	0.320
44-h average DBP	0.316	0.208
44-h systolic blood pressure variability	0.259	0.402
44-h diastolic blood pressure variability	0.135	0.662
Left ventricular end-diastolic volume indexed to body surface area	0.528	0.014
Left ventricular end-systolic volume indexed to body surface area	0.506	0.019
Left ventricular mass indexed to body surface area	0.600	0.005
Cardiac index	−0.210	0.357
Ejection fraction	−0.551	0.010
Ratio of early to late diastolic transmitral flow velocity (E/A)	0.008	0.965
Ratio of early transmitral peak velocity to early diastolic peak annular velocity (E/e′)	0.253	0.162
Left atrial volume index	0.279	0.123