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Acute Kidney Injury

Impact of electronic AKI alert/care bundle on AKI inpatient outcomes: a retrospective single-center cohort study

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Article: 2313177 | Received 21 Sep 2023, Accepted 27 Jan 2024, Published online: 12 Feb 2024

Figures & data

Figure 1. The electronic AKI care plan (AKI-CP). Checkboxes on the left when checked lead to the ordering of specific urine and/or blood tests, denoted by the ‘clipboard’ icon, part of the AKI-CP, e.g., ‘Dipstick Urinalysis’, or ‘Urea and electrolytes, blood’. Text to the right of the ‘pinned note’ icon represent specific advice relevant for the management of AKI part of the AKI-CP, e.g., ‘Consider stopping nephrotoxics (ACE inhibitors/ARBs, diuretics, NSAIDs, antihypertensives, gentamycin, trimethoprim, metformin)’. The text to the right of the ‘document’ and ‘pinned note’ icons under the ‘Links’ heading are links to the local and national guidelines for the management of AKI.

Figure 1. The electronic AKI care plan (AKI-CP). Checkboxes on the left when checked lead to the ordering of specific urine and/or blood tests, denoted by the ‘clipboard’ icon, part of the AKI-CP, e.g., ‘Dipstick Urinalysis’, or ‘Urea and electrolytes, blood’. Text to the right of the ‘pinned note’ icon represent specific advice relevant for the management of AKI part of the AKI-CP, e.g., ‘Consider stopping nephrotoxics (ACE inhibitors/ARBs, diuretics, NSAIDs, antihypertensives, gentamycin, trimethoprim, metformin)’. The text to the right of the ‘document’ and ‘pinned note’ icons under the ‘Links’ heading are links to the local and national guidelines for the management of AKI.

Figure 2. The interruptive electronic alert from the ‘AKI order set’. An example of the interruptive electronic alert from the ‘AKI order set’, which is triggered by AKI stage 2 or above. This alert provides information about the patient’s details, including their name, date of birth, age, location and Medical Records Number (MRN), and suggests that the use initiates the AKI-CP.

Figure 2. The interruptive electronic alert from the ‘AKI order set’. An example of the interruptive electronic alert from the ‘AKI order set’, which is triggered by AKI stage 2 or above. This alert provides information about the patient’s details, including their name, date of birth, age, location and Medical Records Number (MRN), and suggests that the use initiates the AKI-CP.

Figure 3. Utilization of the AKI care plan (AKI-CP) over time.

Figure 3. Utilization of the AKI care plan (AKI-CP) over time.

Table 1. Baseline characteristics of patients by AKI-CP initiation status.

Table 2. Univariable and multivariable adjusted analysis of covariates and all-cause inpatient mortality among AKI events.

Table 3. Progression of AKI stage and length of stay as per AKI-CP initiation.

Table 4. Univariable and multivariable adjusted analysis of covariates associated with change in AKI stage.

Figure 4. Standardized survival curves by initiation of the AKI-CP.

Figure 4. Standardized survival curves by initiation of the AKI-CP.

Table 5. Adjusted Cox-proportional hazard ratios and improvement in restricted mean survival time by completion of the AKI-CP at different timepoints.

Supplemental material

Supplemental Material

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Data availability statement

The data underlying this article cannot be shared publicly due to patient confidentiality requirements as unique patient identifiers were used to ascertain outcomes.