Association of miR-203 Expression with Prognostic Value in Patients with Esophageal Cancer: A Systematic Review and Meta-Analysis

Figures & data

Figure 1. Document retrieval flow chart.

Table 1. Basic features included in the meta-analysis.

Study	Year	Region	Source of samples	Histology	Tumor stage	Cases	Detection method	cut-off value	Results
Okumura	2014	Japan	Tissue	ESCC	I-IV	20	qRT-PCR	2-fold change	OS
Hezova	2015	Czech	Tissue	EAC	NR	22	qRT-PCR	Median	DFS
Qi QF	2016	China	Tissue	ESCC	I-III	50	qRT-PCR	NR	OS
Liu YB	2016	China	Tissue	ESCC	I-IV	119	qRT-PCR	Median	OS
Shao YJ	2017	China	Tissue	EC	NR	169	qRT-PCR	NR	OS
He RQ	2019	China	Tissue	EC	NR	96	NCRPAD	Mean	OS

NCRPAD: non-coding RNA profiling array data; NR: not reported; OS: overall survival; DFS: disease-free survival; EC: Esophageal cancer; ESCC: Esophageal Squamous Cell Carcinoma; qRT-PCR: quantitative Real-time Polymerase chain reaction; EAC: Esophageal adenocarcinoma.

Figure 2. Forest plot of miR-203 expression associated with overall survival of esophageal cancer.

Figure 3. Sensitivity analysis to verify the robustness of the results of overall survival.