Does hospitalization, independent of other treatment, improve severe chronic skin conditions?

Figures & data

Table 1. Summary of published effect of inpatient hospitalization on patients with AD and/or PSO.

Study	Sample Size	Outcome Measures	Results	Treatments
Prospective Cohorts
Schmitt et al.^6	14 AD 22 PSO	EASI/PASI (SEM) VAS score (SEM) DLQI (SEM)	At 3-month follow up: Mean change in EASI/PASI and VAS scores was 12.5 (2.2) and 2.7 (0.5) respectively, (p < 0.001). Mean DLQI decreased at by 9.1 (1.5) (p < 0.001).	Anti-inflammatory treatment including UV therapy, unspecified topical agents
Retrospective Cohorts
Masson et al.^4	56 AD	SCORAD	SCORAD reduced by 50% or more in 65% of patients. SCORAD reduced by 75% in 27% of patients. Mean reduction of SCORAD index was 57.9%.	Daily bath with emollients and chlorhexidine, topical corticosteroids (betamethasone dipropionate or fluticasone propionate cream), antibiotics
Observational Study
Van der Schaft et al.^5	79 AD	SASSAD	At 3-month follow up: SASSAD50 achieved in 79.7% of patients and SASSAD75 achieved in 55.7 % of patients. Mean SASSAD score decrease was 69.0%.	Emollients, topical corticosteroids, oral immunosuppressives, antihistamines and antibiotics

AD: atopic dermatitis; PSO: psoriasis; EASI: eczema area and severity index; PASI: psoriasis area and severity index; SEM: standard error of the mean; VAS: visual analog scale (disease severity); DLQI: dermatology life quality index; SCORAD: SCORing Atopic dermatitis; SASSAD50; Six Area, Six Sign Atopic Dermatitis score reduction of 50%; SASSAD75: Six Area, Six Sign Atopic Dermatitis score reduction of 75%.

Schmitt J, Heese E, Wozel G, et al. Effectiveness of inpatient treatment on quality of life and clinical disease severity in atopic dermatitis and psoriasis vulgaris - a prospective study. Dermatology. 2007;214(1):68–76.

 PubMed Web of Science ®Google Scholar

Masson Regnault M, Hegazy S, Konstantinou MP, et al. Efficacy of hospital inpatient topical treatment for severe adult atopic dermatitis: a retrospective study of 56 patients. Eur J Dermatol. 2017;27(4):418–419.

 PubMed Web of Science ®Google Scholar

van der Schaft J, Keijzer WW, Sanders KJ, et al. Is there an additional value of inpatient treatment for patients with atopic dermatitis? Acta Derm Venereol. 2016;96(6):797–801.

 PubMed Web of Science ®Google Scholar

Data availability statement

The data that support the findings of this study are available in the PubMed database at https://pubmed.ncbi.nlm.nih.gov/. These data were derived from the following resources available in the public domain: https://pubmed.ncbi.nlm.nih.gov/.