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Journal of Dermatological Treatment Volume 34, 2023 - Issue 1
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Case Report

Successful treatment with amoxicillin-clavulanic acid: cutaneous nocardiosis caused by Nocardia brasiliensis

Youqi Jia Department of Clinical Laboratory, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China;b School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, ChinaView further author information
,
Fang Sua Department of Clinical Laboratory, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, ChinaView further author information
,
Xin Honga Department of Clinical Laboratory, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China;c Department of Green Pharmaceutical Collaborative Innovation Center, School of Pharmacy, Zhejiang University of Technology, Hangzhou, Zhejiang, ChinaView further author information
,
Mengyuan Chena Department of Clinical Laboratory, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, ChinaView further author information
,
Yongze Zhua Department of Clinical Laboratory, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, ChinaView further author information
,
Dongqing Chengb School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, ChinaView further author information
&
Yumei Gea Department of Clinical Laboratory, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China;b School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China;c Department of Green Pharmaceutical Collaborative Innovation Center, School of Pharmacy, Zhejiang University of Technology, Hangzhou, Zhejiang, China;d Key Laboratory of Biomarkers and In Vitro Diagnosis Translation of Zhejiang province, Hangzhou, Zhejiang, ChinaCorrespondence[email protected]
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Article: 2229467 | Received 22 Mar 2023, Accepted 04 Jun 2023, Published online: 03 Jul 2023

Figures & data

Figure 1. Skin examination. (A) Initial presentation with three inflammatory pimples and right lower limb erythema, warmth, tenderness. (B) healed lesion leaving dark pigmentation.

Figure 1. Skin examination. (A) Initial presentation with three inflammatory pimples and right lower limb erythema, warmth, tenderness. (B) healed lesion leaving dark pigmentation.

Figure 2. Pathogenic examination. (A) Acid fast staining showed it was weakly acid-fast with a filamentous appearance. (B) Bacterial colonies on rabbit blood agar after incubation at 37 °C for 24 h. (C) Matrix-assisted laser desorption/ionization-time of flight (MALTID-TOF) mass spectrometry showed it was Nocardia brasiliensis.

Figure 2. Pathogenic examination. (A) Acid fast staining showed it was weakly acid-fast with a filamentous appearance. (B) Bacterial colonies on rabbit blood agar after incubation at 37 °C for 24 h. (C) Matrix-assisted laser desorption/ionization-time of flight (MALTID-TOF) mass spectrometry showed it was Nocardia brasiliensis.

Table 1. Antimicrobial susceptibility of the Nocardia brasiliensis by Kirby–Bauer method and Epsilometer test.

Data availability statement

Data available on request from the corresponding author.

Table 1. Antimicrobial susceptibility of the Nocardia brasiliensis by Kirby–Bauer method and Epsilometer test.

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