SARS-CoV-2: an environmental trigger of Darier’s disease?

Figures & data

Figure 1. Extensive keratotic, erythematous, edematous papules and vesicles on the trunk and extremities.

Figure 2. a) Papule of Darier’s disease showing suprabasal acantholysis, with the formation of a small cleft, associated with a thicked stratum corneum, with focal parakeratosis (Haematoxylin-eosin; original magnification 10x); b) Dyskeratotic cells are observed both in the upper malpighian layer and the stratum corneum (corps ronds and grains), floating also in the suprabasal cleft (Haematoxylin-eosin; original magnification 100x); c) Papillary dermis projections covered by a single layer of basal cells extend into the suprabasal cleft. In the superficial dermis is observed mild lymphocytic infiltrate, with rare eosinophils (Haematoxylin-eosin; original magnification 40x).

Data availability statement

Additional data supporting the findings of this manuscript are available upon reasonable request to the corresponding author.