An 8-year follow-up of IgG4-related skin disease presented with generalized ALHE-like eruptions: successful treatment of glucocorticoid and cyclophosphamide

Figures & data

Figure 1. Clinical examination revealed scattered red plaques, papules and nodules on his face (a), limbs (C,D), and trunk (B,C).

Figure 2. Histopathology of the back specimen (A,B) and the nose specimen (D,E) revealed a lymphohistiocytic infiltrate with eosinophil and plasma cell accumulation with numerous vessels. Immunoperoxidase staining for IgG (C) and IgG4 (F) shows more than 50 positively staining plasma cells per high-powered field with an IgG to IgG4 ratio close to 40%.