Comparing Mohs micrographic surgery and wide local excision in the management of head and neck dermatofibrosarcoma protuberans: a scoping review

Figures & data

Figure 1. DFSP. Proliferation of uniform spindle cells in the dermis, separated from epidermis by a border zone. (Courtesy: Dr. Daja Šekoranja).

Figure 2. PRISMA flow chart.

Figure 3. Rate of recurrence of DFSP in head and neck area after Mohs micrographic surgery. Case series.

Table 1. Non-comparative studies of the treatment of DFSP of the head and neck with Mohs micrographic surgery (MMS).

	Author	Year	Total number of patients with DFSP	Mean number of stages	Number of patients with primary/recurrent tumor	Number of patients with DFSP in H&N	Patients with recurrence	Follow-up time (years)
General population	Dawes et al.	1996	24	NR	15/9	6	1	5.1
	Garcia et al.	1996	16	3.3	6/0	3	0	4
	Haycox et al.	1997	10	NR	3/7	5	0	3.5
	Ratner et al.	1997	58	2.4	33/25	13	1	3
	Huether et al.	2001	33	NR	26/7	4	0	3.8
	Nouri et al.	2002	20	2.5	17/3	2	0	1.5
	Ah-Weng et al.	2002	21	1.3	16/5	4	0	3.9
	Snow et al.	2004	29	4.1	21/8	13	0	>5
	Wacker et al.	2004	22	1.6	13/9	7	0	1.8
	Thomas et al.	2007	39	2.3	31/4	3	0	3.2
	Hafner et al.	2008	70	NR	54/16	9	0	5.3
	Nelson et al.	2008	44	2.4	31/11	6	0	2.5
	Hancox et al.	2008	25	1.9		6	0	3.1
	Tan et al.	2011	35	1.5	22/13	6	0	2.4
	Irarrazaval et al.	2012	29	1.4	12/17	3	0	4.7
	Chaput et al.	2013	35	NR	35/0	2	0	3.8
	Loghdey et al.	2014	76	NR	67/9	8	0	4.1
	Martín-Fuentes et al.	2018	33	1.3	37/6	4	0	6.25
	Nieto-Benito et al.	2021	163	NR	105/58	25	0	NA
	Gassenmaier et al.	2021	48	2	35/13	7	2	4.1
	Serra-Guillén et al.	2022	222	1.4	113/111	40	0	10.5
Head and neck population	Tom et al.	2003	9	3.9	7/2	9	0	3.9
	Verbruggen et al.	2018	20	1.2	20/0	20	0	3.1
	González et al.	2021	41	1.6	23/18	41	1	7.7

NR: not reported.

Figure 4. Comparison of rate of recurrence of DFSP in head and neck area after Mohs micrographic surgery. MMS: Mohs micrographic surgery; WLE: wide local excision.

Table 2. Comparative studies between wide local excision (WLE) and Mohs micrographic surgery (MMS) for the treatment of DFSP of the head and neck.

Author	Year	Total number of patients with DFSP	Patients with DFSP in H&N	Patients treated with Mohs surgery	Recurrence in the Mohs surgery group	Follow-up time in the Mohs surgery group (years)	Patients treated with wide local excision	Recurrence in the wide local excision group	Follow-up time in the wide local excision group (years)
DuBay et al.	2004	62	15	7	0	5.2	8	0	4.0
Paradisi et al.	2008	79	9	2	0	5.4	7	2	4.8
Goldberg et al.	2015	41	9	2	0	9.3	7	0	8.7
Lowe et al.	2017	186	33	10	1	4.8	23	11	5.7
Durack et al.	2021	518	51	20	0	NR	31	3	NR

NR: not reported.