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Letter to the Editor

Successful treatment of acrodermatitis continua of Hallopeau by TYK2 inhibitor with every other day

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Article: 2316239 | Received 04 Feb 2024, Accepted 04 Feb 2024, Published online: 22 Feb 2024

Figures & data

Figure 1. (a,b) Clinical findings on initial presentation. (a) and (b) illustrate painful erythema and swelling of the distal digits, nail hyperkeratosis, and detachment.

Figure 1. (a,b) Clinical findings on initial presentation. (a) and (b) illustrate painful erythema and swelling of the distal digits, nail hyperkeratosis, and detachment.

Figure 2. (a) A thick stratum corneum with incomplete keratinization and underlying pustules are seen, and a dense cellular infiltrate is seen in the surrounding area. (b) Numerous neutrophils collect in the upper epidermis from the stratum corneum down to the stratum corneum, forming large pustules. Kogoj’s spongiform pustule is formed in the surrounding epidermis.

Figure 2. (a) A thick stratum corneum with incomplete keratinization and underlying pustules are seen, and a dense cellular infiltrate is seen in the surrounding area. (b) Numerous neutrophils collect in the upper epidermis from the stratum corneum down to the stratum corneum, forming large pustules. Kogoj’s spongiform pustule is formed in the surrounding epidermis.

Figure 3. (a,b) Clinical finding after52 weeks of deucravacitinib treatment. (a) and (b) show complete remission of skin and nail disease.

Figure 3. (a,b) Clinical finding after52 weeks of deucravacitinib treatment. (a) and (b) show complete remission of skin and nail disease.