Figures & data
Figure 1 Effect of exogenous CRF on the plasma concentration of corticosterone in socially isolated rats. Rats were housed in groups or in isolation for 30 days. Data represent the percentage increase in the plasma concentration of corticosterone in the rats given intracerebroventricular (i.c.v.) CRF, relative to the corresponding values for control (saline-injected) rats and are means ± SEM of values from 14 animals. Basal values: group-housed rats, 99 ± 11 ng/ml; isolated rats, 127 ± 16 ng/ml. *P < 0.01 vs group-housed rats (Student's t-test).
Figure 2 Effect of i.p. dexamethasone on the plasma concentration of corticosterone in socially isolated rats. Rats were housed in groups or in isolation for 30 days. Data represent the plasma concentration of corticosterone expressed as a percentage of the corresponding values for control (saline-injected) rats and are means ± SEM of values from 20 animals. Basal values: group-housed rats, 113 ± 10 ng/ml; isolated rats, 131 ± 14 ng/ml. *P < 0.01 vs corresponding control rats; †P < 0.01 vs corresponding group-housed rats (two-way analysis of variance followed by Newman-Keuls test).
