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Research Article

Risk analysis of metformin use in prostate cancer: a national population-based study

, , , &
Article: 2156497 | Received 27 May 2022, Accepted 04 Dec 2022, Published online: 28 Mar 2023

Figures & data

Figure 1. Flow chart of the study cohort.

Patients diagnosed with prostate cancer for the first time from 2012 to 2014 were selected as exclusion criteria. (1) Patients whose death date is not correct; (2) Patients younger than 20 years; (3) Patients with missing data and final subjects were selected.
Figure 1. Flow chart of the study cohort.

Table 1. Descriptive characteristics of the study population with PCa.

Table 2. Overall survival rate.

Figure 2. Kaplan–Meier survival analysis of time to death.

The survival curve during the follow-up period was estimated using the Kaplan-Meier method and the survival between groups was compared with the log Rank ranking test, and the survival rate was significantly different depending on the presence or absence of metformin in the phase survival analysis (p < 0.001).
Figure 2. Kaplan–Meier survival analysis of time to death.

Table 3. Hazard ratios for mortality in PCa patients.

Table 4. Hazard ratios for prostate cancer incidence.

Table 5. Hazard ratio for prostate cancer incidence by the group.

Table 6. Conditional relative 5-year survival.