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Research Article

Primary high-grade urothelial carcinoma of prostate with prostatic hyperplasia: a rare case report and review of the literature

ORCID Icon, , , ORCID Icon, , & show all
Article: 2252102 | Received 12 Jul 2023, Accepted 22 Aug 2023, Published online: 29 Aug 2023

Figures & data

Figure 1. MRI: prostate size was about 57 mm × 50 mm × 54 mm, increased prostatic transitional zone, and surrounding of prostatic duct indicate bar isointense T1 and short T2; posterior of peripheral zone indicate patchy isointense T1 and short T2.

Figure 1. MRI: prostate size was about 57 mm × 50 mm × 54 mm, increased prostatic transitional zone, and surrounding of prostatic duct indicate bar isointense T1 and short T2; posterior of peripheral zone indicate patchy isointense T1 and short T2.

Figure 2. Chest CT: no tumor in the lungs and pleura (a) transverse view and (b) coronal view). (c) Whole body bone scan: no bone metastasis.

Figure 2. Chest CT: no tumor in the lungs and pleura (a) transverse view and (b) coronal view). (c) Whole body bone scan: no bone metastasis.

Figure 3. PET/CT: prostate protruding into the bladder was enlarged, with abnormal increases in glucose metabolism of the local lesion, considered to be a malignant tumor, and hypermetabolic pelvic lymph nodes, which should be considered for metastasis.

Figure 3. PET/CT: prostate protruding into the bladder was enlarged, with abnormal increases in glucose metabolism of the local lesion, considered to be a malignant tumor, and hypermetabolic pelvic lymph nodes, which should be considered for metastasis.

Figure 4. (× 400 HE) The tumor cells exhibited Umbrella or spindle-shaped and were diffusely nests and clumps, cleft formation in partial cells regions, a necrotic area in some areas, with abundant clear cytoplasm, conspicuous nucleoli, mark nuclear atypia, and numerous karyokinesis.

Figure 4. (× 400 HE) The tumor cells exhibited Umbrella or spindle-shaped and were diffusely nests and clumps, cleft formation in partial cells regions, a necrotic area in some areas, with abundant clear cytoplasm, conspicuous nucleoli, mark nuclear atypia, and numerous karyokinesis.

Data availability statement

All data generated or analyzed during this study are included in this published article.