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Research Article

Sexual function and pelvic floor function in men with systemic sclerosis compared to healthy controls: a cross-sectional study

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Article: 2336630 | Received 06 Oct 2023, Accepted 26 Mar 2024, Published online: 07 Apr 2024

Figures & data

Table 1. Sociodemographic characteristics, disease-related clinical and laboratory features of male patients with SSc and healthy controls.

Figure 1. Sexual function and pelvic floor function in men with SSc and healthy controls. (A) According to IIEF, patients with SSc exhibited significantly worse scores in all five domains (Erectile function, Orgasmic function, Sexual desire, Intercourse satisfaction, and Overall satisfaction) compared to healthy controls. (B) Scores in all scales of MSHQ (Erection scale, Ejaculation scale, Satisfaction scale, and Sexual desire/activity scale) were significantly decreased in men with SSc compared to healthy controls. (C) No significant differences were observed between patients with SSc and healthy controls in any of the pelvic floor function domains measured by PFIQ-7. (D) Sexual quality of life (SQoL-M) was significantly decreased in SSc patients compared to healthy individuals. Data are presented as mean (columns) and standard error of the mean (whiskers). *p < 0.05; **p < 0.01; ***p < 0.001; ns: not significant

Figure 1. Sexual function and pelvic floor function in men with SSc and healthy controls. (A) According to IIEF, patients with SSc exhibited significantly worse scores in all five domains (Erectile function, Orgasmic function, Sexual desire, Intercourse satisfaction, and Overall satisfaction) compared to healthy controls. (B) Scores in all scales of MSHQ (Erection scale, Ejaculation scale, Satisfaction scale, and Sexual desire/activity scale) were significantly decreased in men with SSc compared to healthy controls. (C) No significant differences were observed between patients with SSc and healthy controls in any of the pelvic floor function domains measured by PFIQ-7. (D) Sexual quality of life (SQoL-M) was significantly decreased in SSc patients compared to healthy individuals. Data are presented as mean (columns) and standard error of the mean (whiskers). *p < 0.05; **p < 0.01; ***p < 0.001; ns: not significant

Table 2. Sexual function and pelvic floor function in sexually active men with SSc and sexually active healthy controls.

Table 3. Bivariate relationships of sexual function and pelvic floor function with selected clinical and laboratory parameters in men with SSc evaluated by Spearman’s or Pearson’s* correlation coefficient.

Table 4. Multivariate regression analysis predicting sexual function in men with SSc.

Supplemental material

Supplemental Material

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Data availability statement

Individual anonymized participant data will not be shared. Pooled study data, protocol, or statistical analysis plan can be shared upon request at [email protected].