The Relationship of Echinacea purpurea. to the Toxicity of Cadmium

Figures & data

Figure 1 Histology of mouse liver sections after 6 weeks Cd injection at 0.16 mg/kg ip. The arrow indicates metaphase of liver cell mitosis. (Hematoxylin and eosin, original magnification × 40).

Table 1. Geometric mean and 25th–75th percentiles of Cd concentration in various organs and blood of mice from the control group and those injected by Echinacea purpurea. (L.) Moench liquid extract 0.05 LD₅₀ (EP 0.05) and 0.1 LD₅₀ (EP 0.1).

	Group of mice
	Control	EP 0.05	EP 0.1
Heart (µg/g)	0.003	0.004	0.003
	0.002–0.004	0.003–0.005	0.001–0.005
Spleen (µg/g)	0.004	0.006	0.004
	0.003–0.006	0.004–0.008	0.003–0.007
Muscle (µg/g)	0.001	0.002	0.002
	0.001–0.002	0.001–0.004	0.001–0.008
Liver (µg/g)	0.020	0.021	0.024
	0.013–0.029	0.018–0.022	0.020–0.031
Kidneys (µg/g)	0.206	0.078	0.065
	0.141–0.323	0.072–0.085	0.059–0.066
Blood (µg/dl)	0.003	0.029	0.013
	0.001–0.017	0.022–0.047	0.015–0.046

Figure 2 Cd²⁺ concentration in heart, spleen, and muscle of mice after CdCl₂ (0.16 mg Cd/1 kg body mass) and EP (0.125 EP extract/1 kg body mass and 0.25 EP extract/1 kg body mass) injection.

Figure 3 Cd²⁺ concentration in blood, liver, and kidneys of mice after CdCl₂ (0.16 mg Cd/1 kg body mass) and EP (0.125 EP extract/1 kg body mass and 0.25 EP extract/1 kg body mass) injection.

Figure 4 The number of mitotic cells during 6 weeks after CdCl₂ 0.05 LD₅₀ and EP 0.05 and 0.1 LD₅₀ injection.