Antihyperglycemic Activity of Cyamopsis tetragonoloba. Beans on Blood Glucose Levels in Alloxan-Induced Diabetic Rats

Figures & data

Table 1 Effect of C. tetragonoloba. beans, ethanol extract (250 mg/kg, p.o.), on oral glucose tolerance in normal rats^a..

	Blood glucose level (mg/dl)
Sample time (min)	Vehicle (Normal saline)	Gliclazide (25 mg/kg)	Ethanol extract (250 mg/kg)
0	65.00 ± 1.00	62.4 ± 2.17	69.60 ± 2.15
30	96.00 ± 2.30	63.4 ± 2.30	82.80 ± 2.33^NS
90	78.40 ± 2.69	48.0 ± 2.15**	81.00 ± 2.44^NS

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Table 2 Effect of C. tetragonoloba. beans, ethanol extract (250 mg/kg, p.o.), on blood glucose level in normal rats^a..

	Blood glucose level (mg/dl)
Sample time (h)	Vehicle (Normal saline)	Gliclazide (25 mg/kg)	Ethanol extract (250 mg/kg)
0	51.60 ± 2.58	53.40 ± 3.14	57.40 ± 2.29
1	66.40 ± 6.04	38.0 ± 2.70	64.40 ± 0.92^NS
3	71.0 ± 3.60	40.40 ± 2.52	65.60 ± 2.24^NS

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Table 3 Effect of acute treatment of C. tetragonoloba. beans, ethanol extract (250 mg/kg, p.o.), on blood glucose level in alloxan-induced diabetic rats^a..

	Blood glucose level (mg/dl)
Sample time (h)	Vehicle (Normal saline)	Gliclazide (25 mg/kg)	Ethanol extract (250 mg/kg)
0	353.80 ± 2.30	329.00 ± 2.57	357.80 ± 3.61
1	352.60 ± 2.13	315.60 ± 2.70^NS	219.60 ± 2.31
3	349.20 ± 2.08	308.20 ± 2.52^NS	159.40 ± 2.44

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Table 4 Effect of subacute treatment of C. tetragonoloba. beans, ethanol extract (250 mg/kg, p.o., once daily), on blood glucose level in alloxan-induced diabetic rats^a..

	Blood glucose level (mg/dl)
Sample time (Day)	Vehicle (Normal saline)	Gliclazide (25 mg/kg)	Ethanol extract (250 mg/kg)
0	353.80 ± 2.30	329.00 ± 2.57	357.80 ± 3.61
1	352.80 ± 2.13	303.80 ± 2.70^NS	119.40 ± 3.45
3	349.20 ± 2.08	306.40 ± 2.82^NS	175.00 ± 2.09
7	354.40 ± 2.52	308.50 ± 1.89^NS	164.60 ± 2.53
10	356.80 ± 2.06	304.60 ± 2.17^NS	152.40 ± 2.93

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