Evaluation of the Antimycobacterial Activity of Extracts from Plants Used as Self-Medication by AIDS Patients in Thailand

Figures & data

Table 1 Medicinal plants used in antimycobacterial assay.

			% yield
Botanical name (Voucher specimen no.)	Family	Part used	CHCl3 extract	MeOH extract	Water extract
Acanthus ebracteatus. Vahl.	Acanthaceae	Leaf, stem	2.2	5.4	9.0
(SN4501010)
Alpinia galanga. (L.) Willd.	Zingiberaceae	Rhizome	5.6	12.0	7.5
(SN4412030)
Baleria lupulina. Lindl.	Acanthaceae	Leaf	11.0	23.0	10.1
(SN4501001)
Baleria lupulina. Lindl.	Acanthaceae	Stem	1.5	7.2	5.8
(SN450105)
Boesenbergia pandurata. (Roxb.) Schltr.	Zingiberaceae	Rhizome	1.6	10.4	8.4
(SN4412015)
Coccinia grandis. (L.) Voigt	Cucurbitaceae	Leaf	6.3	9.6	13.1
(SN4412050)
Eclipta prostata. (L.) L.	Compositae	Whole plant	5.7	7.5	17.4
(SN4412025)
Gynura pseudochina. (L.) D.C. var. hispida. Thv.	Compositae	Whole plant	ND	ND	ND
(SN4701001)
Murraya paniculata. (L.) Jack	Rutaceae	Leaf	11.3	17.3	8.4
(SN4412040)
Piper betle. L.	Piperaceae	Leaf	16.4	14.7	7.3
(SN4412035)
Piper chaba. Hunter	Piperaceae	Fruit	9.2	5.1	10.5
(SN4412020)
Spilanthes acmella. (L.) Murray	Compositae	Whole plant	2.3	12.3	15.9
(SN4412045)
Zingiber zerumbet. (L.) Roscoe ex Sm.	Zingiberaceae	Rhizome	1.9	4.3	14.1
(SN4412010)

ND, not determined.

Table 2 Minimum inhibitory concentration (MIC) of crude medicinal plant extracts against Mycobacterium tuberculosis. H37Ra.

	MIC (µg/ml)
Botanical name	CHCl3 extract	MeOH extract	Water extract
Acanthus ebracteatus.	1000	1000	1000
Alpinia galanga.	0.12	1000	1000
Baleria lupulina. (leaf)	1000	1000	1000
Baleria lupulina. (stem)	500	1000	1000
Boesenbergia pandurata.	1000	62.5	62.5
Coccinia grandis.	1000	1000	1000
Eclipta prostata.	125	1000	62.5
Gynura pseudochina. var. hispida.	200	1000	1000
Murraya paniculata.	250	1000	1000
Piper betle.	62.5	1000	1000
Piper chaba.	16	125	1000
Spilanthes acmella.	500	1000	1000
Zingiber zerumbet.	125	1000	NA
Rifampin		0.0023
Isoniazid		0.1
Kanamycin		2.5

NA, not applicable.

Table 3 Minimum inhibitory concentration (MIC) of active compounds against Mycobacterium tuberculosis. H37Ra.

Medicinal plants	Active compounds	Activity at 200 µg/ml	MIC (µg/ml)
Alpinia galanga.	1′-Acetoxychavicol acetate	Active	0.024
Piper chaba.	Piperine	Active	50.0