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Research Article

Central Inhibitory Effects of the Methanol Extract of Neorautanenia mitis. Root in Rats and Mice

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Pages 113-120 | Accepted 04 Oct 2004, Published online: 07 Oct 2008

Figures & data

Figure 1 Effects of the methanol extract of N. mitis. root (p.o.) 5 mg/kg (

), 10 mg/kg (
), and 20 mg/kg (
) on spontaneous motor activity in mice. Control group (
) administered distilled water; n = 6, F (3, 23) = 5.73; p < 0.05, compared to control; two-way ANOVA. *Denotes statistical differences.

Figure 1 Effects of the methanol extract of N. mitis. root (p.o.) 5 mg/kg (Display full size), 10 mg/kg (Display full size), and 20 mg/kg (Display full size) on spontaneous motor activity in mice. Control group (Display full size) administered distilled water; n = 6, F (3, 23) = 5.73; p < 0.05, compared to control; two-way ANOVA. *Denotes statistical differences.

Figure 2 Effects of the methanol extract of N. mitis. root (p.o.) 5 mg/kg (

), 10 mg/kg (
), 20 mg/kg (
), and diazepam 1 mg/kg (□) on pentobarbitone-induced hypnosis in rats. Control group (
) administered distilled water; n = 6, F (3, 23) = 12.26; p < 0.05, compared to control; two-way ANOVA. *Denotes statistical differences.

Figure 2 Effects of the methanol extract of N. mitis. root (p.o.) 5 mg/kg (Display full size), 10 mg/kg (Display full size), 20 mg/kg (Display full size), and diazepam 1 mg/kg (□) on pentobarbitone-induced hypnosis in rats. Control group (Display full size) administered distilled water; n = 6, F (3, 23) = 12.26; p < 0.05, compared to control; two-way ANOVA. *Denotes statistical differences.

Figure 3 Effects of the methanol extract of N. mitis. root (p.o.) 5 mg/kg (

), 10 mg/kg (
), 20 mg/kg (
), and diazepam 1 mg/kg (□) on exploratory behavior in rats. Control group (
) administered distilled water; n = 6, F(3, 23) = 4.31; p < 0.05; two-way ANOVA. *Denotes statistical differences.

Figure 3 Effects of the methanol extract of N. mitis. root (p.o.) 5 mg/kg (Display full size), 10 mg/kg (Display full size), 20 mg/kg (Display full size), and diazepam 1 mg/kg (□) on exploratory behavior in rats. Control group (Display full size) administered distilled water; n = 6, F(3, 23) = 4.31; p < 0.05; two-way ANOVA. *Denotes statistical differences.

Figure 4 Effects of the methanol extract of N. mitis. root (p.o.) 5 mg/kg (

), 10 mg/kg (
), and 20 mg/kg (
) on amphetamine-induced hyperactivity in mice. Control group (
) administered distilled water; n = 6, F(3, 23) = 4.05; p < 0.05, compared to control; two-way ANOVA. *Denotes statistical differences.

Figure 4 Effects of the methanol extract of N. mitis. root (p.o.) 5 mg/kg (Display full size), 10 mg/kg (Display full size), and 20 mg/kg (Display full size) on amphetamine-induced hyperactivity in mice. Control group (Display full size) administered distilled water; n = 6, F(3, 23) = 4.05; p < 0.05, compared to control; two-way ANOVA. *Denotes statistical differences.

Figure 5 Effects of the methanol extract of N. mitis. root (p.o.) 5 mg/kg (

), 10 mg/kg (
), and 20 mg/kg (
) on apomorphine-induced hyperactivity in mice. Control group (
) administered distilled water; n = 6, F(3, 23) = 3.97; p < 0.05, compared to control; two-way ANOVA. *Denotes statistical differences.

Figure 5 Effects of the methanol extract of N. mitis. root (p.o.) 5 mg/kg (Display full size), 10 mg/kg (Display full size), and 20 mg/kg (Display full size) on apomorphine-induced hyperactivity in mice. Control group (Display full size) administered distilled water; n = 6, F(3, 23) = 3.97; p < 0.05, compared to control; two-way ANOVA. *Denotes statistical differences.

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