Figures & data
Figure 1 Time course (weekly) of changes in mean arterial pressure (mm Hg) during 5 weeks in sham control, DOCA, ME-30 + DOCA, ME-30, MF-15 + DOCA, and MF-15 treated groups. *p < 0.05 when compared with sham control group. #p < 0.05 when compared with DOCA hypertensive rats. Vertical lines represent SEM, n = 6.
Figure 2 Mean arterial blood pressure (mm Hg) after completion of treatment schedule in (1) sham control, (2) DOCA, (3) ME-30 + DOCA, (4) ME-30, (5) MF-15 + DOCA, and (6) MF-15 treated groups. *p < 0.05 when compared with sham control group. #p < 0.05 when compared with DOCA hypertensive rats. Vertical lines represent SEM, n = 6.
Figure 3 Mean change in blood pressure to noradrenaline in (1) sham control, (2) DOCA, (3) ME-30 + DOCA, (4) ME-30, (5) MF-15 + DOCA, and (6) MF-15 treated groups. *p < 0.05 when compared with sham control rats. Vertical lines represent SEM, n = 6.
Figure 4 Mean change in blood pressure to adrenaline in (1) sham control, (2) DOCA, (3) ME-30 + DOCA, (4) ME-30, (5) MF-15 + DOCA, and (6) MF-15 treated groups. *p < 0.05 when compared with sham control rats. Vertical lines represent SEM, n = 6.
Figure 5 Mean change in blood pressure to 5-HT in (1) sham control, (2) DOCA, (3) ME-30 + DOCA, (4) ME-30, (5) MF-15 + DOCA, and (6) MF-15 treated groups. *p < 0.05 when compared with sham, control and #p < 0.05 when compared with DOCA hypertensive rats. Vertical lines represent SEM, n = 6.
Figure 6 Time course (weekly) of changes in systolic blood pressure (mm Hg) during 7 weeks in control (CoN), F-10, F-10 + ME-100, and ME-100 treated groups. **p < 0.01, ***p < 0.001 when compared with control rats; #p < 0.05 when compared with fructose hypertensive rats. Vertical lines represent SEM, n = 6.
Figure 7 Mean change in blood pressure to 5-HT in (1) Control, (2) F-10, (3) F-10 + ME-100, and (4) ME-100 treated groups. *p < 0.05 when compared with control rats. #p < 0.05 when compared with fructose hypertensive rats. Vertical lines represent SEM, n = 6.
Figure 8 Effect of ME-100 on DRC of 5-HT on isolated rat fundus strip in control (Con), F-10, F-10 + ME-100, and ME-100 treated groups. $: p < 0.001 when compared with control rats. @: p < 0.001 when compared with fructose hypertensive rats. Vertical lines represent SEM, n = 6.
