Figures & data
Figure 1 (a) Tracings show the inhibitory and reversal effects of extract (300 mg/mL) and mevinphos (10−9M), respectively, on Ach-induced contractions of RSS. Control responses to ach (6.6 × 10−9 M to 10.2 × 10−8 M) are shown in A., extract inhibited responses to Ach (1.3 × 10−8 M to 10.2 × 10−9 M) are shown in B., and reversed effects by mevinphos to Ach (same concentrations as controls) are shown in C.. (b) The inhibitory effects of extract (300 mg/mL) and the potentiation effects of mevinphos (10−9 M) on Ach-induced (6.6 × 10−9 M to 10.2 × 10−8 M) contractions of RSS. Data are shown as the mean (±SE) responses (n = 6 per treatment). Responses from both treatments, extract and mevinphos, were significantly different than those of controls (paired t.-tests, p < 0.05).
Table 1.. The percent inhibitory analgesic properties of Mormodica involucrata. and paracetamol on acetic acid writhing response in mice. (Writhing numbers are expressed as mean ± SE, n = 5 per treatment.)
Table 2.. The sedative properties of extract Mormodica involucrata. (55–75 mg/mL) on sleep in mice (n = 10 per treatment)
Table 3.. Lethality of high doses (350–480 mg/kg) of Mormodica involucrata. treatments in mice (n = 10 per treatment)