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Research Article

Study of Furostenol Glycoside Fraction of Tribulus terresteris. on Male Sexual Function in Rats

, , , , &
Pages 191-198 | Accepted 03 Aug 2007, Published online: 07 Oct 2008

Figures & data

Figure 1 High performance liquid chromatogram of TT-FG.

Figure 1 High performance liquid chromatogram of TT-FG.

Figure 2 Male sexual behavior parameters in male rats after acute (1 day) and subacute (7 and 14 days) oral treatment of TT-FG at (▾) 5 mg/kg, (▪) 10 mg/kg (•), 25 mg/kg. Separate groups for vehicle (▪) and standard drug, sildenafil, 5 mg/kg (▵), were also maintained. Data represented are mean number of observations ± SEM in castrated male rats (six per group) analyzed by two-way repeated measure ANOVA on ranks followed by post hoc. Holm-Sidak test. ns, non-significant compared with values of vehicle-treated group on corresponding day. All other values are significant at p. < 0.05.

Figure 2 Male sexual behavior parameters in male rats after acute (1 day) and subacute (7 and 14 days) oral treatment of TT-FG at (▾) 5 mg/kg, (▪) 10 mg/kg (•), 25 mg/kg. Separate groups for vehicle (▪) and standard drug, sildenafil, 5 mg/kg (▵), were also maintained. Data represented are mean number of observations ± SEM in castrated male rats (six per group) analyzed by two-way repeated measure ANOVA on ranks followed by post hoc. Holm-Sidak test. ns, non-significant compared with values of vehicle-treated group on corresponding day. All other values are significant at p. < 0.05.

Figure 3 Male orientational activity in male rats after acute (1 day) and subacute (7 and 14 days) oral treatment of TT-FG at (▾) 5 mg/kg, (▪) 10 mg/kg, (•) 25 mg/kg. Separate groups for vehicle (▪) and standard drug, sildenafil, 5 mg/kg (▵), were also maintained. Data represented are mean number of observations ± SEM in castrated male rats (six per group) analyzed by two-way repeated measure ANOVA on ranks followed by post hoc. Holm-Sidak test. ns, non-significant compared with values of vehicle-treated group on corresponding day. All other values are significant at p. < 0.05.

Figure 3 Male orientational activity in male rats after acute (1 day) and subacute (7 and 14 days) oral treatment of TT-FG at (▾) 5 mg/kg, (▪) 10 mg/kg, (•) 25 mg/kg. Separate groups for vehicle (▪) and standard drug, sildenafil, 5 mg/kg (▵), were also maintained. Data represented are mean number of observations ± SEM in castrated male rats (six per group) analyzed by two-way repeated measure ANOVA on ranks followed by post hoc. Holm-Sidak test. ns, non-significant compared with values of vehicle-treated group on corresponding day. All other values are significant at p. < 0.05.

Figure 4 Effect of TT-FG on serum testosterone levels in male rats after 14 days of treatment of TT-FG. Separate groups for vehicle and standard drug testosterone were also maintained. Figures in parentheses indicate dose in mg/kg. Data represented are mean testosterone level (ng/dL) ± SEM in castrated male rats (six per group) analyzed by one-way ANOVA followed by Bonferroni post hoc test. **p. < 0.05, ***p. < 0.001 as compared with vehicle-treated group.

Figure 4 Effect of TT-FG on serum testosterone levels in male rats after 14 days of treatment of TT-FG. Separate groups for vehicle and standard drug testosterone were also maintained. Figures in parentheses indicate dose in mg/kg. Data represented are mean testosterone level (ng/dL) ± SEM in castrated male rats (six per group) analyzed by one-way ANOVA followed by Bonferroni post hoc test. **p. < 0.05, ***p. < 0.001 as compared with vehicle-treated group.

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