Figures & data
Figure 1 Effect of ET on lipid peroxidation (n = 3). Results are expressed as mean percentage inhibition of lipid peroxidation ± SEM.
Figure 2 Reducing power of ethanol extract of ET, BHT, and BHA (n = 3). Results are expressed as mean of absorbance ± SEM.
Figure 3 Histopathology of normal, CMC plus CCl4, and CCl4 plus ET treated rat liver section (× 100, H&E). Liver section of control rats showed normal hepatic cells with well preserved cytoplasm, prominent nuclei, and nucleoli, and well brought out central vein (A). CMC plus CCl4-treated group showed centrilobular necrosis and broad infiltration of lymphocytes and Kupffer cells were observed. Extension of necrosis bridges to other centrilobular veins were also found in the CMC plus CCl4-treated group (B). Pretreatment of the rats with 500 mg/kg ET showed protection to CCl4-induced liver damage. Liver necrosis was limited to cells around centrilobular veins without the present of necrosis bridges (C).
Figure 4 (A) Effect of different doses of ET on serum ALT level elevation by CCl4 (n = 6). Values are means ± SEM; *** indicates significant difference compared with the CMC plus CCl4-treated group at p < 0.05 and p < 0.01, respectively; # and ### indicate significant differences compared with the control group at p < 0.05 and p < 0.001 respectively. (B) Effect of different doses of ET on serum AST level elevation by CCl4 (n = 6). Values are means ± SEM; ** and *** indicate significant differences compared with the CMC plus CCl4 group at p < 0.01 and p < 0.001, respectively; ### indicates significant difference compared with the control group at p < 0.001.
