Glycemic Properties of Trichosanthes dioica Leaves

Figures & data

Table 1.  Effect of variable doses of Trichosanthes dioica leaf aqueous extract on BGL during FBG test of normoglycemic rats (mean ± SD).

	Blood glucose levels (Mg dl^−1)
	Pre-treatment		Post-treatment (h)
Experimental groups	Treatment (mg kg^− 1 bw)	FBG	2	4	6
Control	Distilled water	75.9 ± 3.6	75.4 ± 4.2	75.7 ± 3.5	75.1 ± 3.9
Extract	250	74.3 ± 3.4	63.9 ± 4.5	57.1 ± 3.7	54.6 ± 3.5*
Extract	500	76.8 ± 4.1	61.2 ± 3.6	55.4 ± 4.2	51.5 ± 3.7*
Extract	750	72.2 ± 3.2	62.3 ± 3.8	54.7 ± 4.3	51.4 ± 3.9*

* P < 0.05 as compared with control.

Table 2.  Effect of variable doses of Trichosanthes dioica leaf aqueous extract on BGL during GTT of normoglycemic rats (mean ± SD).

Blood glucose levels (Mg dl^−1)
Pre-treatment			Post-treatment (h)
Experimental Groups	Treatment (mg kg^− 1 bw)	FBG	0	1	2	3
Control	Distilled water	76.7 ± 3.7	76.1 ± 4.5	112.4 ± 4.1	105.6 ± 4.3	98.7 ± 3.9
Treated 1	250	73.2 ± 3.8	65.4 ± 3.5	88.8 ± 3.7	80.8 ± 4.5	74.1 ± 3.8*
Treated 2	500	74.7 ± 4.1	63.0 ± 3.9	82.1 ± 4.2	75.7 ± 3.6*	68.2 ± 3.9*
Treated 3	750	75.9 ± 3.6	64.7 ± 4.2	84.8 ± 3.6	78.4 ± 3.5*	71.5 ± 3.7*

* P < 0.05 as compared with control.

Figure 1.  Effect of variable doses of Trichosanthes dioica leaf aqueous extract on BGL during GTT in sub-diabetic rats. **P < 0.01 as compared with control. Control: Distilled water, Treated 1: 250 mg kg^{− 1}, Treated 2: 500 mg kg^{− 1}, Treated 3: 750 mg kg^{− 1}, Glibenclamide: 250 mg kg^{− 1}.

Figure 2.  Effect of variable doses of Trichosanthes dioica leaf aqueous extract on BGL during GTT in mild-diabetic rats. **P < 0.01 as compared with control. Control: Distilled water, Treated 1: 250 mg kg^{− 1}, Treated 2: 500 mg kg^{− 1}, Treated 3: 750 mg kg^{− 1}, Glibenclamide: 250 mg kg^{− 1}.