Hypoglycemic activity of Iraqi Rheum ribes root extract

Figures & data

Figure 1.  Effect of Rheum ribes extracts on blood glucose in healthy mice.

Table 1.  Effect of oral administration of extracts of Rheum ribes root on plasma glucose concentration in healthy mice. The values represent the mean ± SEM.

Group	Treatment	Blood glucose levels (mmol/L)
		0 h	1 h	2 h	4 h	24 h
1	Control	9.04 ± 0.37	9.62 ± 0.39	9.28 ± 0.38	7.94 ± 0.43	9.44 ± 0.24
2	Glibenclamide	8.43 ± 0.13	7.43 ± 1.60	6.63 ± 0.44	6.08 ± 1.01	7.55 ± 1.58
3	Extract A	9.24 ± 0.79	10.62 ± 1.60	9.24 ± 1.41	8.54 ± 1.22	7.28 ± 1.19
4	Extract B	8.38 ± 0.44	9.5 ± 0.57	8.36 ± 0.49	7.28 ± 0.68	6.72 ± 1.15
5	Extract C	10.82 ± 0.18	11.1 ± 0.64	9.5 ± 0.89	7.98 ± 0.37	9.26 ± 0.44

Figure 2.  In vitro stimulatory effects of extract (C) on INS-1E cells.

Figure 3.  TLC plate for extract C1 under UV 366 nm; 1-aloe emodin; 2-emodin; 3- physcion; 4- chrysophanol standard compound. (See colour version of this figure online at www.informapharmascience.com/phb).