Effect of tea catechins on erythrocyte Ca⁺⁺-pump in type 2 diabetes mellitus

Figures & data

Figure 1.  Structure of catechins.

Figure 2.  Concentration-dependent effect of tea catechins on erythrocyte membrane Ca⁺⁺-ATPase activity. (A) Normal human: EGCG, EGC show significant (p <0.01) activation of Ca²⁺ ATPase at 10⁻⁵ M concentration. ECG and EC show significant activation only at 10⁻³ and 10⁻⁴ M. (B) Type 2 diabetic patients: EGCG, EGC, ECG, EC show significant activation of Ca²⁺ ATPase at 10⁻³ – 10⁻⁵ M concentration. *Ca⁺⁺ ATPase activity is expressed as μmol of Pi released /h/mg membrane protein at 37°C. Values are mean ± SD.