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Research Article

PolySOD-catalase as a therapeutic agent with antioxidant properties

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Pages 620-623 | Received 16 Mar 2008, Accepted 06 Apr 2008, Published online: 22 Jun 2009

Figures & data

Scheme 1. Relationship between superoxide dismutase (SOD), catalase (CAT), superoxide radical (O2), and hydrogen peroxide (H2O2).

Scheme 1.  Relationship between superoxide dismutase (SOD), catalase (CAT), superoxide radical (O2−), and hydrogen peroxide (H2O2).

Figure 1. Effect of initial glutaraldehyde concentration on recovery of SOD and catalase activities after polymerization..

Figure 1.  Effect of initial glutaraldehyde concentration on recovery of SOD and catalase activities after polymerization..

Figure 2. Stability of different form superoxide dismutase following exposure to xanthine/xanthine oxidase system. Initial glutaraldehyde concentration for polymerization reaction was 0.25%..

Figure 2.  Stability of different form superoxide dismutase following exposure to xanthine/xanthine oxidase system. Initial glutaraldehyde concentration for polymerization reaction was 0.25%..

Figure 3. Plasma circulation time of SOD and catalase in rats. Antioxidant enzyme samples were injected intravenously into anesthetized Sprague-Dawley rats. The activities of SOD (U) and catalase (U) remaining in the plasma were measured as a function of time. Rat plasma before injection was used as the blank for plasma enzyme activity determination. Initial glutaraldehyde concentration for polymerization reaction was 0.25%..

Figure 3.  Plasma circulation time of SOD and catalase in rats. Antioxidant enzyme samples were injected intravenously into anesthetized Sprague-Dawley rats. The activities of SOD (U) and catalase (U) remaining in the plasma were measured as a function of time. Rat plasma before injection was used as the blank for plasma enzyme activity determination. Initial glutaraldehyde concentration for polymerization reaction was 0.25%..

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