Figures & data
Figure 1. The serum gelatinolytic activity in zymography assay. Zone of clear bands corresponds with protease activity at 72 kDa (pro-MMP-2), 92 kDa (pro-MMP-9), 130 kDa (MMP-9 heterodimer) and 200 kDa (MMP-9 homodimer). Pravastatin line represents zymogram after an 18-h incubation with pravastatin 5 μg/mL versus incubation with conventional buffer only (control).
Figure 2. Analysis of serum gelatinase activity. White and gray columns represent the activity of MMP-2 (72 kDa) and MMP-9 (92, 130 and 200 kDa) after incubation without or with pravastatin. Median value and 1st-3rd quartiles. Wilcoxon test.
