Active cytomegalovirus replication in patients with coronary disease

Figures & data

Table I.  Characteristics of patients and controls. Values are given as mean (SD).

Mean values	ACS patients	SA patients	Controls
Age, years	59.2 (6.7)	59.3 (5.3)	60.8 (4.4)
Male/female, n	32/8	39/11	42/8
BMI, kg/m^2	27.1 (3.6) ^*	27.1 (3.9) ^*	25.3 (2.9)
Blood pressure
syst, mm Hg	137 (19)	132 (18)	132 (16)
diast, mm Hg	80 (11)	81 (7)	81 (8)
Current smokers %	40	22	20
Laboratory variables
Total cholesterol, mmol/l	5.1 (0.8) ^#†	4.7 (0.8) ^#	6.1 (1.0)
LDL cholesterol	3.1 (0.8) ^#†	2.6 (0.6) ^#	4.0 (0.9)
HDL cholesterol	1.2 (0.3) ^#	1.2 (0.3) ^§	1.5 (0.5)
Triglycerides	1.9 (0.9) ^#	1.8 (1.1) ^§	1.3 (0.5)
Glucose	4.8 (0.9)	4.9 (0.7)	4.9 (0.7)
Elevated troponin T, >0.05 µg/l (%)	64	–
> 2 significant coronary stenoses (%)	67	76

^*p < 0.05 compared with controls, ^§p < 0.01 compared with controls, ^#p < 0.001 compared with controls, ^†p < 0.001 compared with SA.

Figure 1.  (A) CMV-IgG serological data on CAD patients and controls (C), (B) CMV-RNA data on CAD patients and controls.

Table II.  Cytokines in patients and controls. Values are given as medians (interquartile range).

	ACS patients	SA patients	Controls
Cytokines, pg/ml
IL-6	3.4 (2.2–6.7)*^§	1.8 (1.5–3.2)	1.8 (1.4–2.9)
IL-10	0.9 (0.7–2.0)	0.8 (<0.5–1.2)	1.0 (0.5–1.6)
CRP mg/l	2.5*^† (1.7–8.0)	1.0 (0.6–2.1)	2.0 (1.0–3.3)

*p < 0.001 compared with SA, ^§p < 0.001 compared with controls, ^†p < 0.01 compared with controls.