https://orcid.org/0000-0002-8449-9691View further author information, https://orcid.org/0000-0001-7205-6853View further author information & https://orcid.org/0000-0003-1463-5448View further author informationFigure 1. Combinatorial diversity of symmetric bsAb binder formats increases exponentially with increasing number of parental antibody building blocks. Only a selected set of symmetric tetravalent bsAbs are shown, but the structural search space will become even bigger while also including asymmetric bsAbs or higher valency symmetric bsAbs.
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