Bactericidal activity of different oxovanadium(IV) complexes with Schiff bases and application of chelation theory

Figures & data

Figure 1 Structures of the Schiff bases.

Figure 2 Bactericidal activities of the complexes.

Table I.  Analytical data for the ligands and their VO(IV) complexes^a.

			% Found (Calcd.)
Compounds empirical formula	Formula weight	Colour	C	H	N	S	Metal	M.p. (°C)	μeff. (B.M.)	Yield (%)
H2L	229.21	Yellow	68.06	4.80	6.07	13.92	-	128	-	70
C13H11NOS			(68.11)	(4.79)	(6.10)	(13.99)
A^1	236.16	Yellow	81.32	6.78	11.80	-	-	235	-	72
C16H16N2			(81.36)	(6.77)	(11.85)
A^2	264.18	Yellow	81.80	7.55	10.64	-	-	260	-	76
C18H20N2			(81.83)	(7.57)	(10.60)
A^4	334.24	Yellowish	86.20	5.40	8.42	-	-	235	-	68
C24H18N2		Brown	(86.23)	(5.38)	(8.37)
A^5	187.17	Yellow	70.62	4.75	7.45	17.10	-	>360	-	60
C11H9NS			(70.58)	(4.81)	(7.48)	(17.13)
A^6	201.20	Yellow	71.61	5.47	6.92	15.93	-	>360	-	58
C12H11NS			(71.63)	(5.46)	(6.95)	(15.94)
[VO(L)(A^1)]	530.23	Green	65.65	4.65	7.90	6.00	9.67	>360	1.75	56
C29H25VN3O2S			(65.68)	(4.71)	(7.92)	(6.03)	(9.60)
[VO(L)(A^2)]	558.25	Green	66.75	5.12	7.60	5.79	9.10	>360	1.79	59
C31H29VN3O2S			(66.69)	(5.19)	(7.52)	(5.73)	(9.12)
[VO(L)(A^3)]	465.17	Green	59.31	3.80	12.00	6.85	10.90	>360	1.81	61
C23H18VN4O2S			(59.38)	(3.87)	(12.03)	(6.88)	(10.95)
[VO(L)(A^4)]	628.31	Green	70.70	4.27	6.75	5.02	8.16	>360	1.79	58
C37H27VN3O2S			(70.72)	(4.29)	(6.68)	(5.09)	(8.10)
[VO(L)(A^5)]	481.18	Green	59.96	3.80	5.80	13.37	10.51	>360	1.80	58
C24H18VN2O2S2			(59.90)	(3.74)	(5.82)	(13.30)	(10.58)
[VO(L)(A^6)]	495.19	Green	60.67	4.00	5.68	12.90	10.32	>360	1.82	60
C25H20VN2O2S2			(60.63)	(4.03)	(5.65)	(12.92)	(10.28)

^aH₂L = salicylidene-o-aminothiophenol, A¹ = bis(benzylidene)ethylenediamine, A² = bis(acetophenone) ethylenediamine, A³ = 2,2′- bipyridylamine, A⁴ = bis(benzylidene)-1,8-diaminonaphthalene, A⁵ = thiophene-o-carboxaldeneaniline, A⁶ = thiophene-o-carboxaldene-p-anisidine.

Figure 3 Suggested structure of the oxovanadium(IV) complexes.