Synthesis, antibacterial and antifungal activities of 3-(1,2,4-triazol-3-yl)-4-thiazolidinones

Figures & data

Scheme 1.  Synthesis of compounds.

Table I.  Antibacterial activity of tested compounds (MIC μg/mL).

Compound	S. epidermidis ATCC 12228	S. aureus ATCC 6538
10	78	312
15	156	1250
16	156	–

Table II.  Antifungal activity of tested compounds (MIC μg/mL).

Compound	C. albicans Eskişehir OGU	C. glabrata ATCC 36583
9	200	200
10	100	200
11	100	200
12	200	200
13	200	200
15	200	200
16	200	200
17	200	200
18	200	200
19	200	200
Ketoconazole	50	100