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Original Research

Estimating the lifetime cost of vaccination in 23 European Countries: a modeling study

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Pages 148-160 | Received 16 Nov 2022, Accepted 07 Dec 2022, Published online: 09 Jan 2023

Figures & data

Table 1. Vaccines and number of lifetime doses included as of the January 2022 national immunization programs of 23 European countries*.

Table 2. Cost per dose of vaccine acquisition and administration in 23 European countries.

Figure 1. Individual lifetime costs of A) vaccines and B) vaccination (combined vaccine acquisition and administration costs) in 23 European countries in the two base cases and scenario analysis. Base case, healthy individual: includes all universally funded vaccines from each country’s most recent national immunization program. Base case, individual with underlying conditions: includes all funded vaccines from each country’s most recent national immunization program. Scenario analysis, healthy individual: for all countries, includes universal vaccination against diphtheria, tetanus, pertussis, Haemophilus influenzae type B, hepatitis A, hepatitis B, human papillomavirus, influenza, measles, meningococcal B, meningococcal C/ACWY, mumps, pneumococcal disease, polio, rotavirus, rubella, varicella, and zoster. Universal vaccination against tick-borne encephalitis and tuberculosis was included for countries in which these vaccines were universally funded in the most recent national immunization program. Rabies vaccination was included for the Czech Republic. Overall costs in (B) comprise costs of vaccines plus costs of administration such as clinic visits, national immunization program administration costs, etc.

Figure 1. Individual lifetime costs of A) vaccines and B) vaccination (combined vaccine acquisition and administration costs) in 23 European countries in the two base cases and scenario analysis. Base case, healthy individual: includes all universally funded vaccines from each country’s most recent national immunization program. Base case, individual with underlying conditions: includes all funded vaccines from each country’s most recent national immunization program. Scenario analysis, healthy individual: for all countries, includes universal vaccination against diphtheria, tetanus, pertussis, Haemophilus influenzae type B, hepatitis A, hepatitis B, human papillomavirus, influenza, measles, meningococcal B, meningococcal C/ACWY, mumps, pneumococcal disease, polio, rotavirus, rubella, varicella, and zoster. Universal vaccination against tick-borne encephalitis and tuberculosis was included for countries in which these vaccines were universally funded in the most recent national immunization program. Rabies vaccination was included for the Czech Republic. Overall costs in (B) comprise costs of vaccines plus costs of administration such as clinic visits, national immunization program administration costs, etc.

Table 3. Individual lifetime cost of vaccination in 23 European countries in the two base cases and scenario analysis.

Table 4. Annual per-person cost of vaccine acquisition and vaccination and per-capita costs of all-cause hospitalization and anti-infective medications in 23 European countries.

Supplemental material

Supplemental Material

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