The clinical significance of a positive Amnisure test™ in women with term labor with intact membranes

Figures & data

Figure 1. Study population.

Table I.  Demographics and intra-partum characteristics

Characteristics	No labor	Labor without clinical ROM			p
	(Group 1; n = 125)	Amnisure(−) (Group 2; n = 56)	Amnisure(+) (Group 3; n = 25)	Labor with clinical ROM(Group 4; n = 30)
Maternal age (yr, mean ± SD)	30.3 ± 3.5	30.3 ± 4.0	30.0 ± 3.6	30.1 ± 3.7	NS
Maternal age ≥35 yr (n (%))	14 (11.2)	9 (16.1)	4 (16)	3 (10.0)	NS
Gestational age at admission (weeks, mean ± SD)	39.8 ± 1.2	39.8 ± 0.9	39.9 ± 0.8	39.6 ± 0.9	NS
Cervical dilatation at admission (cm, mean ± SD)	0.4 ± 0.6*	2.2 ± 1.3	2.4 ± 1.0	2.1 ± 1.7	<0.001
Use of regional analgesia (n (%))	56/99 (56.6)^†	32 (57.1)	16 (64.0)	17 (56.7)	NS
Use of oxytocin (n (%))	76/99 (76.8)^†*	21 (37.5)	9 (36.0)	10 (33.3)	<0.001
Pre-pregnancy BMI (kg/m^2, mean ± SD)	20.9 ± 2.9^‡	20.4 ± 3.2	20.1 ± 4.4	19.4 ± 2.0	<0.05
Pre-pregnancy BMI > 29 kg/m^2 (n (%))	2/123 (1.6)	2/51 (3.9)	1/23 (4.3)	0/29 (0)	NS
Gestational age at delivery (weeks, mean ± SD)	40.0 ± 1.2^§	39.9 ± 0.9	39.9 ± 0.8	39.6 ± 0.9	<0.001
Birthweight (g, mean ± SD)	3296 ± 460	3205 ± 331	3244 ± 397	3253 ± 393	NS
Birthweight ≥4 kg (n (%))	7 (5.6)	0 (0)	1 (4.0)	0 (0)	NS
Cesarean delivery (n (%))	18/99 (18.2)^†	4 (7.1)	1 (4.0)	3 (10.0)	NS

^†Number of corresponding cases among patients who were planned for induction (n = 99). Twenty-six patients who were admitted for elective cesarean section, were excluded from analysis.

*p < 0.05 compared with the other groups (Groups 2, 3 and 4).

^‡p < 0.05 compared with Groups 3 and 4.

^§p < 0.05 compared with Group 4.

Figure 2. Survival analysis of admission-to-delivery interval, according to the presence of clinical ROM and results of Amnisure test™[Group 2, in labor without clinical ROM and results of the Amnisure with a negative Amnisure test™: median, 9.79 h (range, 2.32–33.07); Group 3, in labor without clinical ROM with a positive Amnisure test™: median, 6.88 h (range, 1.18–15.98); Group 4, in labor with clinical ROM: median, 5.58 h (range, 1.80–33.47)]. NS, not significant.