The levels of peripheral blood TNF-α, Decorin and neutrophils MAPK1 mRNA levels of patients with preeclampsia and their clinical significance

Figures & data

Figure 1. Flow chart for recruitment of study participants.

Table 1. Comparison of baseline data and blood TNF-α, DCN and MAPK1 mRNA in pregnant women.

Clinical/biochemical parameters	Early-onset (n = 26)	Late-onset (n = 55)	Control group (n = 50)	F/χ²	T	p
Maternal age (years)	28.64 ± 4.70	28.39 ± 4.50	27.93 ± 5.04	0.394	—	.601
BMI (kg/m²)	27.36 ± 1.28	27.75 ± 1.43	28.03 ± 1.57	0.187	—	.883
Diastolic blood pressure (mmHg)	112.06 ± 8.54	108.35 ± 8.49	85.60 ± 7.43	6.374	—	.005
Systolic blood pressure (mmHg)	170.33 ± 12.46	164.29 ± 11.80	125.63 ± 6.31	9.870	—	.001
Number of pregnancies	2.34 ± 0.82	2.51 ± 0.76	2.39 ± 0.81	0.093	—	.924
Number of births	1.39 ± 0.52	1.24 ± 0.47	1.30 ± 0.42	0.224	—	.790
Gestational week of childbirth	32.86 ± 2.39	36.92 ± 2.81	39.40 ± 2.03	5.842	—	.006
TNF-α(µg/L)	1.92 ± 0.16	1.59 ± 0.13	0.97 ± 0.14	—	48.356^a	<.001
					108.973^b	<.001
					16.859^c	<.001
DCN(ng/mL)	0.90 ± 0.20	0.69 ± 0.15	0.42 ± 0.12	—	23.927^a	<.001
					48.399^b	<.001
					8.977^c	<.001
MAPK1 mRNA	1.05 ± 0.16	0.85 ± 0.12	0.62 ± 0.08	—	28.845^a	<.001
					53.885^b	<.001
					10.932^c	<.001

Note. ^aEarly-onset group compared to control group; ^blate-onset group compared to control group; ^cearly-onset group compared to late-onset group.

Figure 2. Box plot and correlation of DCN, MAPK1 mRNA and TNF-α levels in peripheral blood of patients with preeclampsia.

Data availability statment

The datasets supporting the conclusions of this article are included within the manuscript. The demanders may contact the corresponding author.