Fluid overload in newborns undergoing abdominal surgery: a retrospective study

Figures & data

Table 1. Baseline patient characteristics and surgical data.

Demographic variables	Median [IQR] or n (%)
Number	60
Gestational age (completed weeks)	29 [25–36]
Birth weight (grams)	1240 [721–2871]
SGA	9 (15)
Mode of delivery – vaginal	22 (36)
Inborn	31 (51)
Pre-operation sepsis	12 (20)
Pre-operation PDA	24 (40)
Days of life at surgery	6 [3–12]
Perioperative fluid administration
Intraoperative volume of bolus fluid (mL/kg)^a	40 [24–61]
Postoperative volume of bolus fluid (mL/kg)	45 [19–90]
Surgical procedure
Stoma	7 (11.7)
Stoma + resection	27 (45)
Resection	15 (25)
Reanastomosis	9 (15)
Drainage	4 (6.7)
Postoperative diagnosis
NEC	14 (23)
Small bowel obstruction	27 (45)
Large bowel obstruction	10 (16)
Small bowel perforation	26 (43)
Large bowel perforation	3 (5)
Postoperative max weight change
Within 3-postoperative days (n = 48)^b	6% [3–13]
Within 7-postoperative days (n = 48)^c	11% [5–17]
Outcomes
In-hospital mortality	8 (13.3)
Days of mechanical ventilation (invasive ventilator support)	4 [2–20]
Days of invasive and noninvasive ventilator support	10.5 [2–81]
BPD (n = 59)	20 (33.9)
Need for inotropes	22 (36)
Postoperative sepsis	8 (13.3)
Post-operation volume of blood product transfusion (mL/kg) (n = 46)	15 [0–43.8]
AKI	4 (6.7)
Raised serum Cr concentration (n = 30)	2 (6.7)
Urine output <1mL/kg/hr	3 (5)
Grade 3,4 IVH/ PVL	9 (15)

SGA: small for gestation age; PDA: patent ductus arteriosus; NEC: necrotizing enterocolitis; AKI: acute kidney injury; BPD: bronchopulmonary dysplasia; IVH: intraventricular hemorrhage; PVL: periventricular leukomalacia.

^aIntraoperative bolus fluid includes colloid and crystalloid fluids given.

^b[Highest weight within post-op day 1–3 – post-op day 0]/postoperative day 0.

^c[Highest weight within post-op day 1–7 – post-op day 0]/postoperative day 0.

Figure 1. Correlation between 3-day postoperative weight change and duration of invasive ventilator support.

Data availability statement

The database for this research article is not available because of identifiable patient particulars in a relatively small number of patients.