The association of hyperuricemia and maternal and fetal outcomes among pregnant women: a meta-analysis

Figures & data

Figure 1. Flowchart of the literature search.

Table 1. Baseline features and quality assessment of included studies.

Author	Year	Country	Study design	Number of participants	Age of patients (years)	UA in case and control groups	PIH in case and control groups	DIC in case and control groups	Preterm birth in case and control groups	LBW in case and control groups	SGA in case and control groups	NOS score
Isezuo	2008	Nigeria	Cross-sectional	90	19.8 ± 3.9	10.4 ± 2.7 mol/L; 4.4 ± 0.8 mol/L	38/45; 6/45	NR	NR	NR	NR	7
Lin	2018	China	Case control	180	33.1 ± 2.5	NR	NR	3/137; 0/43	26/137; 3/43	25/137; 3/43	NR	6
Marrs	2018	USA	Cohort study	556	25.9	NR	111/335; 80/201	NR	NR	NR	23/335; 14/201	8
Liu	2019	China	Cross-sectional	6715	30 ± 4.3	NR	NR	NR	61/416; 354/5276	52/416; 208/5266	64/416; 297/5276	6
Paula	2019	Brazil	Cohort study	374	27 ± 7.5	5.32 ± 1.45 mg/dL; 6.92 ± 1.93 mg/dL	16/329; 17/45	NR	NR	NR	NR	8
Jummaat	2020	Malaysia	Cohort study	79	32 ± 5.1	NR	2/40; 1/39	NR	24/40; 11/39	NR	NR	8
Ayankunle	2021	Nigeria	Case control	110	31.4 ± 4.8	11.4 ± 1.6 mg/dL; 5.1 ± 1.1 mg/dL	39/55; 4/55	NR	NR	NR	NR	6

NOS: the Newcastle-Ottawa scale; NR: not reported; DIC: disseminated intravascular coagulation; LBW: low birth weight; PIH: pregnancy-induced hypertension; SGA: small for gestational age.

Figure 2. Forest plot of the analysis of pregnancy-induced hypertension.

Figure 3. Forest plot of the analysis of preterm birth.

Figure 4. Forest plot of the analysis of low birth weight.

Figure 5. Forest plot of the analysis of small for gestational age.

Data Availability statement

The datasets generated and/or analyzed during the current study are available in the article.