Serotype distribution, antimicrobial resistance, and molecular characterization of group B Streptococcus isolates from Chinese pregnant woman

Figures & data

Figure 1. Distributions of serotyping and erythromycin-resistant genes in GBS isolates. (A) Serotype distribution of 311 GBS isolates; (B) distribution of erythromycin resistance genes in 237 GBS isolates.

Table 1. GBS antimicrobial susceptibility patterns.

	Susceptibility
Antibiotics	S (%)	I (%)	R (%)
Erythromycin	16.72% (52/311)	7.07% (22/311)	76.21% (237/311)
Clindamycin	23.47% (73/311)	12.54% (39/311)	63.99% (199/311)
Levofloxacin	41.16% (128/311)	8.04% (25/311)	50.80% (158/311)
Tetracycline	12.54% (39/311)	6.43% (20/311)	81.03% (252/311)

S: susceptible; I: intermediate; R: resistant.

Figure 2. Distributions of sequence types in 145 GBS isolates.

Table 2. The relationship between main serotypes and STs of GBS.

Serotypes	STs					P
	ST1 (n = 8)	ST10 (n = 27)	ST12 (n = 18)	ST17 (n = 9)	ST19 (n = 42)
Ia	5 (62.5%)	17 (62.96%)	12 (66.67%)	0	1 (2.38%)	<.01
Ib	3 (37.5%)	9 (33.33%)	5 (27.78%)	0	6 (14.29%)	.092
III	0	1 (3.70%)	1 (5.56%)	9 (100.00%)	35 (83.33%)	<.01

Due to the small number of remaining genotypes, only the main serotypes and sequence types are listed in the table. STs: sequence types.

Data availability statement

Raw data were generated at Beijing Obstetrics and Gynecology Hospital, Capital Medical University. Derived data supporting the findings of this study are available from the corresponding author ZC and YZ on request.